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College Football Picks: Ohio State vs Indiana Vegas Odds, Prediction (Oct 23th)

  • Ohio State has won four straight games
  • Indiana has lost three of their last four
  • Ohio State 3-0 in Big Ten play

Last season, Indiana was up there with Ohio State as a contender to win the Big Ten. And these two teams combined for one of the more entertaining games of the college football season last year.

This season, these teams are heading in very different directions, as Ohio State has been exceptional in Big Ten conference play, while Indiana has struggled to find its footing for the duration of this season.

Ohio State Buckeyes vs Indiana Hoosiers Schedule

  • Where: Memorial Stadium, Bloomington, IN
  • When: Saturday, October 23, 7:30PM ET
  • How to Watch: ABC

Ohio State vs Indiana Vegas Odds

Ohio State vs Indiana Preview

Ohio State Playing For Playoff Hopes

When Ohio State lost to Oregon in non-conference play, they knew they would have to be virtually perfect the rest of the way to have a chance to make the College Football Playoff. So far, they have done that, winning their last four games since the loss to Oregon, with two of those four wins coming in conference play. Now at 3-0 in the Big Ten, Ohio State still controls its own destiny as far as their playoff hopes are concerned.

Ohio State Buckeyes defensive lineman J.T. Tuimoloau (44) brings down Rutgers Scarlet Knights quarterback Cole Snyder (15) during the fourth quarter of a NCAA Division I football game between the Rutgers Scarlet Knights and the Ohio State Buckeyes on Saturday, Oct. 2, 2021 at SHI Stadium in Piscataway, New Jersey.

Cfb Ohio State Buckeyes At Rutgers Scarlet Knights
Ohio State Buckeyes defensive lineman J.T. Tuimoloau (44) brings down Rutgers Scarlet Knights quarterback Cole Snyder (15) during the fourth quarter of a NCAA Division I football game between the Rutgers Scarlet Knights and the Ohio State Buckeyes on Saturday, Oct. 2, 2021 at SHI Stadium in Piscataway, New Jersey. Cfb Ohio State Buckeyes At Rutgers Scarlet Knights

It is worth noting that the recent surge from the Buckeyes has been aided largely by a huge step down in quality of competition in recent weeks. After losing to Oregon, the Buckeyes have beaten Tulsa, Akron, Rutgers, and Maryland. This week, the Buckeyes are in for the biggest test they’ve faced since falling to the Ducks, even if Indiana has struggled through their first six games of the season.

Indiana Seeking First Big Ten Win

After last year’s incredible campaign, expectations were high for the Indiana Hoosiers coming into this year, and the Hoosiers have not lived up to those expectations. Indiana is 2-4 on the season and has yet to pick up a win over a Big Ten opponent. But the Hoosiers did show last year that they can hang with Ohio State and will look to recapture that magic in this primetime game at home.

Oct 16, 2021; Bloomington, Indiana, USA; Indiana Hoosiers running back Stephen Carr (5) is tackled by multiple Michigan State Spartans during the second half at Memorial Stadium. Spartans win 20-15. Mandatory Credit: Marc Lebryk-USA TODAY Sports
Oct 16, 2021; Bloomington, Indiana, USA; Indiana Hoosiers running back Stephen Carr (5) is tackled by multiple Michigan State Spartans during the second half at Memorial Stadium. Spartans win 20-15. Mandatory Credit: Marc Lebryk-USA TODAY Sports

In order to have a chance against Ohio State, the Indiana offense will need to put up big numbers against an Ohio State defense that has struggled at times this year. The Buckeyes have looked good on defense against subpar opponents over their last four games. But a quarterback with the ability of Michael Penix Jr. could expose their vulnerabilities all over again.

Ohio State vs Indiana Prediction & Pick

Who will win tonight’s CFB game:

Ohio State is going to beat the Indiana Hoosiers to move to 4-0 in the Big Ten on the season. But Indiana is more than capable of covering the spread if they can make this game into a track meet.

Ohio State’s defense will be put to the test here, and the Hoosiers will cover the three-touchdown spread despite the likelihood that Ohio State gets the victory.

Expert Pick Against The Spread:

  • Indiana +21
Ayden loves sports. There is no doubt about that. He is a walking calendar when it comes to the latest events in sports. He has grown into the passion of writing about them and settled into his role as a writer after many freelancing jobs. He can write about any sport out there! This is the guy!

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