Free MLB Picks: Dodgers vs Padres Prediction, Odds (April 16)

  • Dodgers (11-2) bring best record in baseball into series
  • The Padres (9-5) Fernando Tatis Jr. will be activated off of the 10-day IL
  • Possible NLCS preview

The Dodgers and Padres will battle in the most anticipated series of the 2021 MLB season. Los Angeles has looked every bit the part of the best team in baseball so far this season. The Dodgers +34 run differential is easily the best in baseball.

San Diego has been good as well. The Padres run differential of +17 is third in the National League and fourth-best in all of baseball.

Dodgers vs Padres Schedule

  • Where: PetCo Park, San Diego, CA
  • When: Friday, April 16, 10:10pm ET
  • How to Watch: Local Broadcast Stations

Dodgers vs Padres Odds

Dodgers vs Padres Preview

The Dodgers are coming in red hot. They have won six in a row and 11 of their last 12. They have given up only 12 runs during the six-game winning streak.

The Padres split a four-game series with the Pittsburgh Pirates after sweeping the Texas Rangers. San Diego’s offense should get a boost with Tatis Jr. returning from the IL.

Dodgers Offense Looks Unstoppable

Los Angeles has combined for a team OPS of .876 early in the season. The team has a slash line of .285/.380/.495 with 18 homers and 31 doubles.

Walker Buehler (1-0, 1.50 ERA) will be making his third start of the season. In his 12 innings, he has allowed ten hits with no walks and eight strikeouts.

Apr 15, 2021; Los Angeles, California, USA; Los Angeles Dodgers pitcher David Price (right) is congratulated by right fielder Mookie Betts (center) and second baseman Max Muncy after the game against the Colorado Rockies at Dodger Stadium. The Dodgers defeated the Rockies 7-5.  Mandatory Credit: Kirby Lee-USA TODAY Sports
Apr 15, 2021; Los Angeles, California, USA; Los Angeles Dodgers pitcher David Price (right) is congratulated by right fielder Mookie Betts (center) and second baseman Max Muncy after the game against the Colorado Rockies at Dodger Stadium. The Dodgers defeated the Rockies 7-5. Mandatory Credit: Kirby Lee-USA TODAY Sports

The Dodgers have never faced San Diego starter, Ryan Weathers. Los Angeles has not been nearly as good against lefties with a team OPS of .753. Justin Turner has crushed left-handed pitching this season with a slash line of .467/.529/1.067.

Padres Pitching Elite

San Diego’s pitching staff has combined for an ERA of 2.38 and a WHIP of 1.03. Weathers (1-0, 1.50 ERA) will be making his first start of the season after coming out of the bullpen for three appearances.

Wil Myers and Eric Hosmer have been the best two regulars, with both having an OPS over 1.000. Myers is slashing .333/.429/.643, and Hosmer is at .340/.421/.600.

Apr 15, 2021; Pittsburgh, Pennsylvania, USA; San Diego Padres shortstop Ha-Seong Kim (left) and second baseman Jake Cronenworth (right) celebrate after defeating the Pittsburgh Pirates at PNC Park. San Diego won 8-3. Mandatory Credit: Charles LeClaire-USA TODAY Sports
Apr 15, 2021; Pittsburgh, Pennsylvania, USA; San Diego Padres shortstop Ha-Seong Kim (left) and second baseman Jake Cronenworth (right) celebrate after defeating the Pittsburgh Pirates at PNC Park. San Diego won 8-3. Mandatory Credit: Charles LeClaire-USA TODAY Sports

San Diego has struggled against Buehler in past meetings. They have a team OPS of .515 in 42 plate appearances. Trent Grisham is 2 for 3 with a homer of the the young right-hander.

Dodgers vs Padres Prediction and MLB Pick

Weathers is not stretched out, so it will be a bullpen game for San Diego. Weathers have been very effective, but three innings is probably the max he can go.

The Dodgers have not hit lefties nearly as well, so Weathers should have some success if he can avoid letting Turner beat him. Look for Adrian Morejon to get a lot of work this weekend as well to see if the Dodgers’ struggles against left-handers continue.

I like the Padres on the five-inning line if you can get them at +140 or better. I like the Dodgers for the full game and the under eight as both pitching staffs have been lights out of late.

Padres 4 – Dodgers 3

Expert Pick(s):

  • Under 8
Alex has covered huge sporting events for various websites and publications. He has attended football European Championships, Rugby League and Union World Cups, and the Paralympics. Alex is dedicated to giving the most insightful tips for VegasOdds readers and specialises in horse racing, soccer, golf and basketball.

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