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NFL Week 6 Predictions, Odds, Schedule for Every Game

Oct 7, 2021; Seattle, Washington, USA; Seattle Seahawks quarterback Geno Smith (7) scrambles beyond the grasp of Los Angeles Rams defensive lineman Mike Hoecht (96) during the fourth quarter at Lumen Field. Mandatory Credit: Joe Nicholson-USA TODAY Sports

Joe Nicholson-USA TODAY Sports

Tampa Bay Buccaneers (4-1) vs Philadelphia Eagles (2-3)

Schedule

Odds

spread
Thu 10/14, 8:20 PM VegasONLINEVegas
Eagles +7.0-120+7.0-120+7.0-120+7.0-120+2.0-113+4.0-110
Buccaneers -7.0+100-7.0+100-7.0+100-7.0+100-2.0-107-4.0-110
Last odds movement: Oct 15, 3:33 am ET

It’s hard to see this one being a close encounter, especially since Tampa Bay managed to shake off the Brady/Belichick circus with a convincing demolition of the Dolphins. Jalen Hurts has shown enough to suggest he can be competitive in most games with this offense, but nobody can run on this Bucs defense and that puts even more pressure on him.

The short week will also play into Brady’s hands due to his experience, and the Bucs will justify their heavy favorite tag with the win.

Predicted Winner: Tampa Bay Buccaneers

Miami Dolphins (1-4) vs Jacksonville Jaguars (0-5)

Schedule

Odds

spread
Sun 10/17, 9:30 AM VegasONLINEVegas
Jaguars +2.5-110+1.5-110+2.5-110+2.5-105-0.5+105-3.0+150
Dolphins -2.5-110-1.5-110-2.5-110-2.5-115+0.5-125+3.0-182
Last odds movement: Oct 17, 6:33 pm ET

Two dumpster fire teams in different ways just now. Jacksonville needs to make a decision on Urban Meyer soon as the speculation about the lack of respect from the players continues to grow, while it’s not like the results are going to save him either.

Miami may have Tua back at QB for this game as he’s touted to return from injury, but Brian Flores is also going to come under fire soon if they can’t turn this around.

The Jags are simply too much of a mess to win this one, but it might be an ugly W for the Dolphins to give them hope of getting this season back on track.

Predicted Winner: Miami Dolphins

Green Bay Packers (4-1) vs Chicago Bears (3-2)

Schedule

Odds

spread
Sun 10/17, 1:00 PM VegasONLINEVegas
Bears +2.5-110+6.0-110+6.0-110+6.0-115+2.0-110+3.0+105
Packers -2.5-110-6.0-110-6.0-110-6.0-105-2.0-110-3.0-125
Last odds movement: Oct 17, 7:55 pm ET

Are the Bears the most disrespected team with a winning record just now? They’ve turned things over to Justin Fields for good and did get an impressive win over the Raiders in Week 5, while they could move on to the same record as the Packers with a win in this one.

The problem is that Aaron Rodgers appears to be back to his best and there’s no stopping this Green Bay offense, so the Packers will find a way to make it 5-1.

Predicted Winner: Green Bay Packers

Cincinnati Bengals (3-2) vs Detroit Lions (0-5)

Schedule

Odds

spread
Sun 10/17, 1:00 PM VegasONLINEVegas
Lions +3.0-115+3.0-110+3.5-115+4.0-110+2.5-120+3.5-105
Bengals -3.0-105-3.0-110-3.5-105-4.0-110-2.5+100-3.5-115
Last odds movement: Oct 17, 7:34 pm ET

It’s easy to see this Bengals team finishing with a winning record this season, although it may be that they don’t quite win the games against the better teams, but they are too strong to be upset by the Lions.

That will depend on the health of Joe Burrow as he was shaken up on Sunday night, while the Lions do look like a team who have to be taken seriously as they are fighting for a win in every game.

Cincinnati will still have too much for them here.

Predicted Winner: Cincinnati Bengals

Houston Texans (1-4) vs Indianapolis Colts (1-4)

Schedule

Odds

spread
Sun 10/17, 1:00 PM VegasONLINEVegas
Colts -6.5-120-11.5-110-10.5-110-11.0-110-6.5-130-4.5-154
Texans +6.5+100+11.5-110+10.5-110+11.0-110+6.5+110+4.5+125
Last odds movement: Oct 17, 6:34 pm ET

This will be a battle of two 1-4 teams, but you still get the feeling that Indy are much better than the record suggests, while Houston deserve to be exactly where they are.

Davis Mills bounced back with a strong performance against the Patriots but it’s hard to tell how much of that was down to defensive breakdowns, while the Colts should’ve beaten the Ravens and managed to throw that away.

Predicted Winner: Indianapolis Colts

Kansas City Chiefs (2-3) vs Washington Football Team (2-3)

Schedule

Odds

spread
Sun 10/17, 1:00 PM VegasONLINEVegas
Washington +3.5-120+6.5+100+7.0-125+6.5-115+6.5-115+3.5-105
Chiefs -3.5+100-6.5-120-7.0+105-6.5-105-6.5-105-3.5-115
Last odds movement: Oct 17, 7:55 pm ET

All is not well in Kansas City, and it’s hard to see them going to the Super Bowl based on current form. The defense cannot stop a thing, while Patrick Mahomes has started to see some of his wayward throws being intercepted rather than broken up, and they just don’t have enough to keep up with how bad the defense is just now.

WFT aren’t exactly coming into this on a hot streak either as their highly touted defense is yet to show up, but if they can get things moving then they could really pile on the misery for Andy Reid and his team in Week 6.

Predicted Winner: Washington Football Team

Los Angeles Chargers (4-1) vs Baltimore Ravens (4-1)

Schedule

Odds

spread
Sun 10/17, 1:00 PM VegasONLINEVegas
Ravens -0.5-105-2.5-120-3.0+100-2.5-110+0.5-110-2.5-110
Chargers +0.5-115+2.5+100+3.0-120+2.5-110-0.5-110+2.5-110
Last odds movement: Oct 17, 7:34 pm ET

How can you pick against this Ravens team just now? They’ve had every conceivable bit of bad luck in the injury department and should be having a down year, but they keep coming back from impossible positions to win.

The problem this week is the Chargers who are quickly becoming the new darlings of the league, and they should dethrone the Chiefs for the division title if things keep up.

This will be high scoring and probably close between two outstanding QB’s in great form, but Justin Herbert doesn’t need to carry the entire team like Jackson does, and that will make the difference here.

Predicted Winner: Los Angeles Chargers

Los Angeles Rams (4-1) vs New York Giants (1-4)

Schedule

Odds

spread
Sun 10/17, 1:00 PM VegasONLINEVegas
Giants +3.5+100+7.5-110+8.5-110+7.5-110+4.0-109+7.5-110
Rams -3.5-120-7.5-110-8.5-110-7.5-110-4.0-111-7.5-110
Last odds movement: Oct 17, 7:55 pm ET

The Giants look set to struggle for another year, especially since Saquon Barkley picked up another injury and might not be ready for the Rams in this one.

Los Angeles are still figuring some things out on offense as Matt Stafford gets used to his new system and receivers, but there’s not a lot to like about the Giants just now and this one won’t even be close.

Predicted Winner: L.A rams

Minnesota Vikings (2-3) vs Carolina Panthers (3-2)

Schedule

Odds

spread
Sun 10/17, 1:00 PM VegasONLINEVegas
Panthers -0.5+105+2.5-110+2.0-110+2.5-105+1.0+100+6.0-222
Vikings +0.5-125-2.5-110-2.0-110-2.5-115-1.0-120-6.0+180
Last odds movement: Oct 17, 10:34 pm ET

Things change very quickly in this league, and it’s very possible that Carolina will go from being an unbeaten team with playoff potential to a .500 team in double-quick speed.

The Panthers are building an incredible defense, but Stephon Gilmore won’t be eligible to play until Week 7 after his trade from the Patriots.

The Vikings only just squeaked past Detroit and they aren’t scoring a lot of points just now, so this looks like a chance for the Panthers to get themselves back on track.

Predicted Winner: Carolina Panthers

Arizona Cardinals (5-0) vs Cleveland Browns (3-2)

Schedule

Odds

spread
Sun 10/17, 4:05 PM VegasONLINEVegas
Browns -2.5-105-3.5+100-3.0+105-3.5-105-3.5-117-4.0-105
Cardinals +2.5-115+3.5-120+3.0-125+3.5-115+3.5-103+4.0-115
Last odds movement: Oct 17, 10:55 pm ET

Arizona weren’t at their explosive best against San Francisco, but they are still 5-0 and they’ll fancy their chances of putting up points on Cleveland after they let 47 go against the Chargers.

Arizona’s defense is often overlooked because of how good Kyler Murray and his troops have been, but they do have enough to shut down this Browns offense too.

We may not see 80+ points in this one, but expect Arizona to keep on rolling.

Predicted Winner: Arizona Cardinals

Dallas Cowboys (4-1) vs New England Patriots (2-3)

Schedule

Odds

spread
Sun 10/17, 4:25 PM VegasONLINEVegas
Patriots +2.5+100+3.0+100+3.5+100+3.5-120+3.5-104+3.5-115
Cowboys -2.5-120-3.0-120-3.5-120-3.5+100-3.5-116-3.5-105
Last odds movement: Oct 17, 11:34 pm ET

It’s often said that winning in New England can be a real litmus test for a potential contender, but that’s only if you look at the name rather than the current iteration of Bill Belichick’s team.

The Pats can’t stop the run or the pass, so Dallas have all the weapons to roll in here and put up a lot of points if they can get off to a fast start.

The only thing to be wary of is that this Pats defense did step up to limit Brady (with the help of some heavy rain) and they might do the same here.

The Cowboys should still emerge with the victory and leave New England 0-4 at home this season.

Predicted Winner: Dallas Cowboys

Las Vegas Raiders (3-2) vs Denver Broncos (3-2)

Schedule

Odds

spread
Sun 10/17, 4:25 PM VegasONLINEVegas
Broncos -2.5-115-5.0-110-4.5-110-4.5-105-4.0-105-5.5-110
Raiders +2.5-105+5.0-110+4.5-110+4.5-115+4.0-115+5.5-110
Last odds movement: Oct 17, 11:34 pm ET

If there is such a thing as a “back on track” game in the NFL then this is it for both teams, as they need to arrest their recent slide after a bright opening to their seasons.

The Raiders have looked poor on offense in their last two outings while the defense has given up too many points, and Denver should have enough at home to get their season back on track.

Predicted Winner: Denver Broncos

Seattle Seahawks (2-3) vs Pittsburgh Steelers (2-3)

Schedule

Odds

spread
Sun 10/17, 8:20 PM VegasONLINEVegas
Steelers -5.0-105-5.5-110-5.0-110-5.0-105-1.5-107-3.0-120
Seahawks +5.0-115+5.5-110+5.0-110+5.0-115+1.5-113+3.0+100
Last odds movement: Oct 18, 3:34 am ET

These are two names that we expect to see in the playoffs every year, but one of them is going to be 2-4 after Week 6 and that’s hard to bounce back from when they play in extremely competitive divisions.

Seattle will be without Russell Wilson so it will be fun to see what Geno Smith can do when a team has a chance to prepare for him, while Pittsburgh continues to underwhelm on offense but they do have a defense that can take over a game.

Seattle’s defense is also poor, and that gives the edge to the Steelers here.

Predicted Winner: Pittsburgh Steelers

Buffalo Bills (4-1) vs Tennessee Titans (3-2)

Schedule

Odds

spread
Mon 10/18, 8:15 PM VegasONLINEVegas
Titans +6.0-105+6.0-110+6.5-110+6.5-115+6.0-113+6.5-110
Bills -6.0-115-6.0-110-6.5-110-6.5-105-6.0-107-6.5-110
Last odds movement: Oct 19, 1:34 am ET

We all wondered if Buffalo’s status as early-season favorites was a massive error when they lost to the Steelers in Week 1, but they are back to their best on both sides of the ball and do look like the real deal yet again.

The Titans can never be counted out but they have been predictable when Julio Jones and A.J Brown were injured, but if they are able to return for this one then it opens up the playbook and makes this a more interesting game.

It may be a close one, but we can’t pick against Buffalo here.

Predicted Winner: Buffalo Bills


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