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Premier League Predictions: Vegas Odds, Preview & Picks (Matchday 2)

  • Premier League Matchday 2 is on the program this coming weekend
  • There are 10 games on the schedule Friday through Monday
  • Check out our top Premier League predictions below!

As the second week of the 2022-23 soccer season approaches, we are going to give our Premier League predictions.

The new round gets underway on Saturday, with its final game scheduled for Monday. Some of those games are supposed to be real barnburners, most notably the one between Chelsea and Tottenham on Sunday.

Fun is guaranteed for Premier League fans, but what about bettors? We think there’s a lot of money to be made in the EPL Matchday 2, which is why we’ve decided to cover all 10 matchups, sharing our top Premier League predictions along the way.


Premier League Matchday 2 Schedule

  • When: Saturday, August 13-Monday, August 15
  • Where: Various stadiums around England
  • How to Watch: NBC Sports/Peacock

Aston Villa vs Everton Vegas Odds

Both teams have zero points after one round of the Premier League, but it’s Aston Villa that should be worried more. It’s because the Villans lost to the EPL newcomers AFC Bournemouth in round 1. It was 2-0 for the team that was a +300 pre-game underdog.

Aston Villa need to do way better in Matchday 2, but the trouble is that this Saturday, they’re locking horns with an even stronger opponent. The team in question is Everton, which did struggle last season, but which definitely has plenty of talent on its roster.

It’s not going to be easy, but Aston Villa have no other option but to go out and try to grab all three points. It’s going to be hard, but we have faith in these guys.

Premier League Predictions:


Arsenal vs Leicester City Vegas Odds

After a 2-0 win on the road against Crystal Palace, Arsenal are coming home to Emirates Stadium in London. That’s where they usually play great, especially when their opponents are the Foxes from Leicester – Arsenal have lost just one game to Leicester City since the 1990s.

This is not going to be a walk in the park for the Gunners, but we can see them win all three points on Saturday.

Premier League Predictions:


Brighton and Hove Albion vs Newcastle United Vegas Odds

On Matchday 1, Brighton beat Manchester United 2-1 at Old Trafford. It was the biggest upset of the whole round, considering that the Seagulls were +550 underdogs before the kickoff.

What happened that day is that Pascal Groß took advantage of Man United’s sloppy defending twice in the first half. The Red Devils did try to fight back, especially in the second half, but Brighton’s defense did a fine job.

Can they do something similar against Newcastle on Saturday? Probably not as the Magpies are going to take this game very seriously. They’re coming to South Coast with the main goal of not losing the game. That said, a draw would suit them just fine.  

Premier League Predictions:


Manchester City vs Bournemouth Vegas Odds

The reigning Premier League champions are the biggest favorites of the round, with the odds as short as -1667.

There are many reasons why that is the case, starting with the fact that they got the most expensive roster in the Prem, while next opponent is almost on the opposite end of the spectrum – Bournemouth’s squad is second from the bottom when player value is concerned.  

Another reason why soccer bookmakers expect an easy win for Manchester City is that the game is played on their turf. Etihad Stadium is the place where Pep Guardiola’s men went 15-2-2 (47 points) last season, scoring 58 goals and conceding just 15 in 19 home games.

Premier League Predictions:


Southampton vs Leeds United Vegas Odds

Southampton was the team to suffer the heaviest defeat on Matchday 1. The Saints lost to Tottenham Hotspur 4-1 in London. Truth be told, everyone expected to see something like that happen. It’s just that Southampton’s players aren’t as good as those playing for Tottenham.

This time, however, Southampton is taking on an opponent they seem capable of beating. In fact, the Saints did beat Leeds the last time they met at St. Mary’s Stadium. Still, it wasn’t a dominant win – they won 1-0 thanks to the goal scored by Armando Broja, who’s now playing for Chelsea.

Premier League Predictions:


Wolves vs Fulham Vegas Odds

Aleksandar Mitrovic – the big Serbian scored twice against Liverpool last weekend, winning one point for Fulham. Can he do the same against Wolves? Well, he hasn’t done anything like that before, at least not in the Premier League. Mitrovic played four times against Wolves in the Premier League, but failed to score even a single goal.

Actually, it’s not just him. His entire team had a bad experience with Wolves. In the top English flight, they are 0-1-3 against Wolves. They did beat them once in the Championship, but what’s interesting is that they’re without a single win over this team in games played in Wolverhampton.  

Premier League Predictions:


Brentford vs Manchester United Vegas Odds

Erik ten Hag’s reign at Manchester United started with a shocking loss, and it’s now up to the Red Devils to try to bounce back. In the second round of the Prem, they’re taking on Brentford, a team they beat both times last season.

SEE ALSO: Erik ten Hag at Man United 2022-23 Prop Bets

Can they do it again? Definitely.

Not only do they have the manpower to pull it off, but they also have the motivation to do so. Failing to win two times in a row against mediocre opponents is something that just mustn’t happen to such a big club as Man United.

Premier League Predictions:


Nottingham Forest vs West Ham Vegas Odds

Nottingham Forest started their Premier League adventure with a 2-0 loss to Newcastle last weekend. It was an expected loss, considering that Tricky Trees have the least valuable squad in the Prem. Oddsmakers expect them to lose again, this time, to West Ham.

Obviously, West Ham needs to be thought of as the favorites, but the thing is that this is going to be the first time in the 21st century that Nottingham Forest are playing a Premier League game on their turf. That said, you can be sure that each of their players is going to give his utmost on the pitch. Still, that probably isn’t going to be enough to win them points.

Premier League Prediction:


Chelsea vs Tottenham Hotspur Vegas Odds

The biggest game of Matchday 2 is a London Derby. It might not be the biggest derby from England’s capital, but both Chelsea and Tottenham look amazing in the 2022-23 season. Both started their campaign with a win – Chelsea beat Everton 1-0 on the road; Tottenham destroyed Southampton 4-1 at home.

Chelsea won each of the previous three duels with Tottenham, but this time, we could see a whole different story. The thing is that things look different in Chelsea’s squad now, especially in the attacking department.

The Blues are without a classic striker, with Romelu Lukaku returning to Italy and Timo Werner moving back to RB Leipzig.

Meanwhile, Tottenham have made their roster even stronger over the last couple of months, while also keeping the core of their team intact.   

Premier League Prediction:


Liverpool vs Crystal Palace Vegas Odds

Fulham messed up Jurgen Klopp’s plans in the first round, but the Reds from Liverpool have a brilliant chance to prove that the 2-2 draw was nothing but a glitch. On Monday, they’re welcoming Crystal Palace at Anfield, the place where they beat this opponent every single time in the previous five games.

Oddsmakers think they’re going to do it again, giving just -500 on Liverpool. It seems that the real question in this game isn’t who’s going to win, but whether it’s going to be a blowout win for Liverpool? We think it’s going to.

Premier League Predictions:

Annie is a seasoned veteran in sports betting and has been working in the industry for over 7 years. Her goal of educating others and sharing her knowledge on the topic has brought her to VegasOdds.com where she regularly contributes to our cornerstone guides and news to help readers improve their sports betting game. If you don’t find her writing, you can bet she’ll be studying sports stats!

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