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Premier League Predictions: Vegas Odds, Preview & Picks (Matchday 6)

  • Premier League Matchday 6 brings us 10 interesting matchups this weekend
  • Check out our top EPL Round 6 picks in the preview below!

If you’re in search of some Premier League predictions, look no further – VegasOdds has you covered!

Matchday 6 in the new 2022-23 season brings us some super-exciting matchups.

On Saturday, September 3, there are eight EPL games on the program, some of which look like real barnburners. The first game of the day is the 261st edition of the Merseyside Derby (Everton vs Liverpool), while a few hours later, two London derbies kick off – Chelsea vs West Ham and Tottenham vs Fulham.

The EPL Matchday 6 wraps up on Sunday, September 4. Only two games are on the program that day, but in this case, it’s not about quantity but quality. This goes especially for the final game of the round – Manchester United vs Arsenal.

Knowing all this, one can only feel excited about the upcoming weekend. If you’d like to take your excitement to a whole new level, the trick is to place some Premier League bets. To help you make the right betting choices, we’ve prepared this EPL Matchday 6 preview, in which we share our predictions for all 10 games.


Everton vs Liverpool Vegas Odds

Since Jurgen Klopp became Liverpool manager, this team’s record in the Merseyside Derby is 9-5-1 (W-D-L). Knowing that Everton players have been horrible since the start of the 2022-23 Premier League season, it seems very likely that Klopp’s boys will win again.

Leading soccer sportsbooks agree, giving the Vegas odds of just -250 on Liverpool. If that’s not a great betting value in your eyes, we got an alternative for you.

Betting on Mohamed Salah to score at least one goal against Everton comes with a price of +110. The reason why that’s our prediction is that he wasn’t among the scorers in Liverpool’s previous two games, in which the Reds put away a total of 11 goals. This is especially strange considering that Salah is the man who’s created more goal chances than anyone else in the Prem.

One final fact to convince you to back Salah to score on Saturday is that by doing that, he’d leapfrog Steven Gerrard in the list of Liverpool’s top scorers in the Premier League era. That sure seems like enough of a motivation for ‘The Egyptian King‘ to give his utmost in Round 6.

Premier League Predictions:


Brentford vs Leeds United Vegas Odds

This game looks destined to finish in a tie. These two play a similar style of soccer, which involves a lot of running and numerous battles in the center of the pitch. This explains why most of their previous duels saw not too many goals. In fact, we saw “under 2.5” happen in seven of the previous ten Brentford vs Leeds games.

We expect something similar to happen this Saturday as well, even though both teams have been playing well in the offense in the 2022-23 EPL season. For example, Brentford scored four times against Manchester United in the second round, while Leeds beat Chelsea 3-0 in Round 3.

Knowing all this, a risk-loving bettor might want to put some on “Brentford vs Leeds correct score 1-1.” This bet comes with the Vegas odds of +650.

Premier League Predictions:


Chelsea vs West Ham Vegas Odds

The Blues just have to bounce back after a shocking loss to Southampton last Tuesday. Beating West Ham won’t be easy, but Chelsea will have their fans to cheer them on from the stands of Stamford Bridge.

Image by danielgalvez-333 from Pixabay

Stamford Bridge is the stadium where Chelsea has a 14-5-2 record since 2000. We expect to see them get to their 15th home win over the Hammers in the 21st century this Saturday.

Premier League Predictions:


Nottingham Forest vs Bournemouth Vegas Odds

Here’s a clash of two teams that played in the Championship last season and which are among the main relegation candidates in the EPL 2022-23 season.

Both teams suffered a couple of humiliating losses lately. AFC Bournemouth lost 9-0 to Liverpool a week ago, while Nottingham Forest got blown out 6-0 by Manchester City on Wednesday. As a result, both are now licking their wounds and are hoping another disaster doesn’t happen anytime soon.

That said, a draw seems like the outcome that would suit well both of them.

Premier League Predictions:


Newcastle United vs Crystal Palace Vegas Odds

If you compare Newcastle and Crystal Palace player-by-player, you’ll see that they’re very similar in terms of quality. However, our prediction for this EPL game is that the hosts will win. The reason is that Newcastle players are fabulous when playing at St. James’ Park.

The Magpies have lost just two home games in the Premier League this year, both of which happened in the previous edition of the Prem. The opponents they lost to are Manchester City and Liverpool – the teams that finished in the top two spots in the EPL table in 2021-22.

When it comes to the 2022-23 season, Newcastle’s home record is 1-1-0, with a 2-0 win over Nottingham Forest and a 3-3 draw with Manchester City.

Premier League Predictions:


Tottenham Hotspur vs Fulham Vegas Odds

The Cottagers are probably the biggest overachievers in the 2022-23 season. As a reminder, Fulham came from the Championship and won eight points in the fires five rounds. These guys won two and drew two games so far while suffering just one loss.

The man they have to thank for this is their striker Aleksandar Mitrovic. The 6’3 200-pound Serbian has scored five goals so far, but we don’t think he’s going to do the same against the Spurs. Why? Because Tottenham’s defense has some big and strong center backs that look capable of handling Mitrovic.

Premier League Predictions:


Wolves vs Southampton Vegas Odds

Wolves have scored only 2 goals so far this season, which is just embarrassing for a team with players like Raul Jimenez, Adama Traore, Gonzalo Guedes, and others on the roster.

Luckily for them, they got a chance to improve their offensive stats on Saturday when they welcome Southampton at Molineux Stadium in Wolverhampton. The Saints famously have a very leaky defense, which conceded a total of 67 goals in 38 games last season.

Premier League Predictions:


Aston Villa vs Manchester City Vegas Odds

Pep Guardiola’s men look unstoppable right now. The Sky Blues are 4-1-0 this season with a score differential of 19-5. Their scoring leader is Erling Haaland, the man who’s coming off back-to-back hat-tricks.

If he scores a hat-trick again, he’s going to become the first Premier League player to do so in three straight games. It’s a big ask, but we’re sure he’s going to try it. Maybe he won’t score three times, but we can see him put away at least one goal for sure.

Premier League Predictions:


Brighton vs Leicester City Vegas Odds

The Foxes are in trouble – after five rounds of the Premier League, they’re sitting at the very bottom of the table with just one point.

To be fair to Leicester City, their schedule has been tough, but they did drop points against some weaker teams as well (e.g., Southampton). Getting to the winning track is a must if they want to keep Brendan Rodgers as their boss.

The Irishman is the no.1 candidate to be the next EPL manager to lose the job, with the odds of just -200. Knowing this, winning all three points on Sunday is a must for the former Premier League champions.

Premier League Predictions:


Manchester United vs Arsenal Vegas Odds

The biggest game of Matchday 6 is the one that’s played on Sunday afternoon at Old Trafford. That’s where Manchester United welcomes the only team EPL team that still has a 100% win rate in the 2022-23 season.

The team in question is Arsenal, whose record is 5-0 with a score difference of 13-4. It’s impressive, sure, but there is a caveat. The Gunners still haven’t faced such a strong opponent as Man United.

Despite a nightmare start to the season, the Red Devils look good now. Plus, they seem like a team that is going to take a couple of giants down this season. In fact, they already did it against one giant – Liverpool.

We expect something similar to happen against Arsenal as well.

Premier League Predictions:

Annie is a seasoned veteran in sports betting and has been working in the industry for over 7 years. Her goal of educating others and sharing her knowledge on the topic has brought her to VegasOdds.com where she regularly contributes to our cornerstone guides and news to help readers improve their sports betting game. If you don’t find her writing, you can bet she’ll be studying sports stats!

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