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UEFA Champions League 2021: Vegas Odds, Picks for Every Game in Week 1

  • Champions League returns with Chelsea looking to retain their title
  • Man City and PSG among the favorites as they hunt glory for the first time
  • Sheriff Tiraspol make their debut in the group stages

The Champions League is back for another season, but there have been multiple changes that make this even more interesting than usual. Cristiano Ronaldo has returned to Man United who will be looking to do much more than get out of the group stages this year, PSG have brought in Lionel Messi to help them in their quest for glory, while Man City will look to go one better.

Sevilla vs RB Salzburg

Schedule

  • Where: Ramon Sanchez Pizjuan, Seville, Spain
  • When: Tuesday, September 24, 12:45PM ET

Odds

Match ResultOdds
Sevilla-150
Salzburg+375
Draw+320

Prediction

Even though we like RB Salzburg because of its youth and potential, Sevilla is a more experienced team that knows how to play at home. Also, the Spanish team has better individuals at the moment, and we simply can’t imagine seeing any other outcome here but their victory.

Predicted Result: Sevilla wins

Young Boys vs Manchester United

Schedule

  • Where: Stade de Suisse Wankdorf, Bern, Switzerland
  • When: Tuesday, September 24, 12:45PM ET

Odds

Match ResultOdds
Young Boys+700
Manchester United-275
Draw+400

Prediction

Cristiano Ronaldo is in the house, which means that the Red Devils’ ambitions are to win in every match now. Truth to be told, United was a massive favorite even before Ronaldo’s comeback, and they were supposed to win without the Portuguese. In this case, their triumph is cemented.

Predicted Result: Manchester United Wins

Villarreal vs Atalanta

Schedule

  • Where: Estadio de la Cerámica, Villarreal, Spain
  • When: Tuesday, September 24, 3:00 PM ET

Odds

Match ResultOdds
Villarreal+145
Atalanta+175
Draw+260

Prediction

The Europa League winners are in the UCL after a long time, and they hope to at least advance to the next stage. On the other side, Atalanta has played a notable role in the most prominent European championship in the last couple of years. We give a slight edge to the home team here because La Dea’s players are obviously tired from the previous EURO 2020.

Predicted Result: Villarreal Wins

Malmo FF vs Juventus

Schedule

  • Where: Eleda Stadion, Malmo, Sweden
  • When: Tuesday, September 24, 3:00 PM ET

Odds

Match ResultOdds
Malmo+600
Juventus-225
Draw+360

Prediction

Despite not starting the season well and playing three games in Serie A without a win, Juventus’ triumph against Malmo shouldn’t be questioned. The Old Lady is a far better team, and we are backing up the guests victory in Sweden.

Predicted Result: Juventus Wins

Chelsea vs Zenit

Schedule

  • Where: Stamford Bridge, London, England
  • When: Tuesday, September 24, 3:00 PM ET

Odds

Match ResultOdds
Chelsea-550
Zenit+1800
Draw+550

Prediction

The UEFA Champions League champions start their title defense at home, facing Zenit St. Petersburgh. The guests are the Russian league winners but are huge underdogs in this game. Chelsea started the EPL strong, looking very confident, and in our opinion, they will win Tuesday’s event without any troubles.

Predicted Result: Chelsea Wins

Dynamo Kyiv vs Benfica

Schedule

  • Where: NSK Olimpijs’kyj, Kyiv, Ukraine
  • When: Tuesday, September 24, 3:00 PM ET

Odds

Match ResultOdds
Dynamo Kyiv+230
Benfica+130
Draw+225

Prediction

This is a match between two very similar teams so it could be a cagey affair, so it wouldn’t be a surprise if both open their campaign with a low-scoring draw here.

Predicted Result: Draw

Lille vs Wolfsburg

Schedule

  • Where: Stade Pierre Mauroy, Villeneuve-d’Ascq, France
  • When: Tuesday, September 24, 3:00 PM ET

Odds

Match ResultOdds
Lille+160
Wolfsburg+175
Draw+230

Prediction

Both Lille and Wolfsburg are an interesting team without big stars, but with many experienced and solid players. They like to play open and offensive football, and regardless of the result, want to attack, but it’s to tough to pick a winner between the two so a draw looks more likely.

Predicted Result: Draw

Barcelona vs Bayern Munich

Schedule

  • Where: Camp Nou, Barcelona, Spain
  • When: Tuesday, September 24, 3:00 PM ET

Odds

Match ResultOdds
Barcelona+250
Bayern Munich+100
Draw+290

Prediction

Barcelona is in trouble. The team is now without Messi, they are winning but with lots of problems in the back, while on the other side, Bayern scored 21 goals in the past three matches. In general, we believe that the Germans are in much better shape, and despite playing at Camp Nou, they should post a win.

Predicted Result: Bayern Wins

Besiktas vs Borussia Dortmund

Schedule

  • Where: Vodafone Arena, Istanbul
  • When: Wednesday, September 15, 12:45PM ET

Odds

Match ResultOdds
Besiktas+450
Borussia Dortmund-167
Draw+320

Prediction

The Turkish champions meet Borussia Dortmund at Vodafone Arena. The only thing we are certain of regarding this match is high efficiency. The hosts are very offensive-minded, the same as the Millionaires who have Haaland upfront. Therefore, a pulsating draw could be played out here.

Predicted Result: Draw

Sheriff Tiraspol vs Shakhtar Donetsk

Schedule

  • Where: Sheriff Stadium, Tiraspol, Transnistria
  • When: Wednesday, September 15, 12:45PM ET

Odds

Match ResultOdds
Sheriff+350
Shakhtar-120
Draw+260

Prediction

Sherriff is debuting in the UEFA Champions League. Reaching this stage is a massive success for the team from Moldova, but they won’t be able to post notable results anymore. Shakhtar is a much better team, and we strongly advise betting on the Miners’ victory.

Predicted Result: Shakhtar Wins

Manchester City vs RB Leipzig

Schedule

  • Where: Etihad Stadium, Manchester, England
  • When: Wednesday, September 15, 3:00PM ET

Odds

Match ResultOdds
Man City-350
RB Leipzig+1000
Draw+450

Prediction

We all saw that RB isn’t at the same level as in the past few years. They’ve lost many important players, plus their head coach, which took a toll on their performances. Manchester City, meanwhile, continued at the same pace as before, and the Citizens should win this one easily.

Predicted Result: Man City Wins

Atletico Madrid vs FC Porto

Schedule

  • Where: Estadio Wanda Metropolitano, Madrid, Spain
  • When: Wednesday, September 15, 3:00PM ET

Odds

Match ResultOdds
Atletico Madrid-163
Porto+600
Draw+250

Prediction

Atletico defeated Espanyol in 90+10 minutes, which was a massive boost before this event. Porto has a respectable squad, but we don’t think that they can endanger the home team. Diego Simeone’s side knows how to play these types of matches, and we predict them to win.

Predicted Result: Atletico Wins

Club Brugge vs PSG

Schedule

  • Where: Jan Breydelstadion, Bruges, Belgium
  • When: Wednesday, September 15, 3:00PM ET

Odds

Match ResultOdds
Club Brugge+1200
PSG-450
Draw+550

Prediction

Messi begins his UCL odyssey with PSG in Brugge. The Saints are massive favorites against the hosts, who are a very talented and offensive-minded unit. The Parisians will win, that is for sure, and while doing so we expect them to score many goals.

Predicted Result: PSG Wins

Liverpool vs AC Milan

Schedule

  • Where: Anfield, Liverpool, England
  • When: Wednesday, September 15, 3:00PM ET

Odds

Match ResultOdds
Liverpool-188
AC Milan+500
Draw+333

The last two games between these teams were in the UCL finals, back in 2005 and 2007. Since then, they haven’t met, and a lot of things have changed. For instance, Liverpool is mighty now, and Milan can’t compete with the Reds, especially at Anfield Road. Simply, we don’t see the hosts wasting a single point here.

Predicted Result: Liverpool Wins

Inter Milan vs Real Madrid

Schedule

  • Where: San Siro, Milan, Italy
  • When: Wednesday, September 15, 3:00PM ET

Odds

Match ResultOdds
Inter+145
Real Madrid+180
Draw+250

Prediction

The replay of last year’s group stage matches. Inter is in much worse shape now, losing its best players and a head coach as well. Real showed some signs of recovery, but they, too, are vulnerable. The result could go either way, but a share of the spoils looks likely.

Predicted Result: Draw

Sporting CP vs Ajax

Schedule

  • Where: Jose Alvalde, Lisbon, Portugal
  • When: Wednesday, September 15, 3:00PM ET

Odds

Match ResultOdds
Sporting+188
Ajax+140
Draw+250

Prediction

Sporting and Ajax are pretty close teams when looking at their quality. They both love to attack and both defenses could be liable to conceding a few goals, but it’s hard to pick between them and a draw is the play here.

Predicted Result: Draw

Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.

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