Italy Serie A Vegas Odds and Betting Guide
Serie A is the elite championship of Italian professional soccer and one of the most popular soccer leagues in the world. It’s been around for 128 years and it keeps on bringing joy to sports fans from all over the world.
This is the league where some of the world’s best teams compete. They have three European champions, numerous UEFA Cup/Europa League winners and many more international trophies. Needless to explain the influence of the Italian national team on world soccer.
The top tier of Italian soccer is always full of excitements, which is no surprise knowing that this is one of the toughest leagues on the planet.
Latest Serie A Picks and Predictions – Gameweek 5
All eyes are on Olimpico in Rome, where Roma hosts Inter Milan. This is the derby of the week, because these two teams occupy the top of the Serie A standings. Roma looks well, for the moment Il Lupi seem like the only team that could challenge Inter and compete with Nerazzurri for the Calcio title.
Juventus squares off with Atalanta in Turin, in a small northern derby. Both the Old Lady and La Deal lost last weekend and need three points in this contest. AC Milan looks to bounce back following three games without a win, and they have the perfect chance to do so. Lecce comes to San Siro and is according to the odds, a complete underdog.
Beneath are the best picks for this round.
Serie A Round 5 Predictions: Best Bets, Match Preview & Top Odds
Apart from this we have a Serie A Gameweek 5 schedule, with picks for each event of this round.
| Date | Time (ET / CEST) | Fixture | Pick |
| Fri, Sep 18 | 2:45 PM ET / 20:45 CET | Monza vs. Sassuolo | Both Teams to Score |
| Sat, Sep 19 | 9:00 AM ET / 15:00 CET | Udinese vs. Cagliari | Under 2.5 Goals |
| Sat, Sep 19 | 9:00 AM ET / 15:00 CET | Bologna vs. Torino | Bologna |
| Sat, Sep 19 | 12:00 PM ET / 18:00 CET | AS Roma vs. Inter Milan | Both Teams to Score |
| Sat, Sep 19 | 2:45 PM ET / 20:45 CET | Venezia vs. Lazio | Lazio |
| Sun, Sep 20 | 6:30 AM ET / 12:30 CET | Fiorentina vs. Napoli | Both Teams to Score |
| Sun, Sep 20 | 9:00 AM ET / 15:00 CET | Parma vs. Genoa | Under 2.5 Goals |
| Sun, Sep 20 | 9:00 AM ET / 15:00 CET | Frosinone vs. Como 1907 | Both Teams to Score |
| Sun, Sep 20 | 12:00 PM ET / 18:00 CET | Juventus vs. Atalanta | Under 2.5 Goals |
| Sun, Sep 20 | 2:45 PM ET / 20:45 CET | AC Milan vs Lecce | AC Milan |
Best Sportsbooks for Betting on Serie A
Serie A Winners Odds
The most popular of all futures considers the Calcio winners. You can find the Serie A Winners Odds here.
Serie A – Europe’s 2nd-Strongest Soccer League
As per UEFA’s league coefficient, Serie A is ranked second among European league based on the performances of Italian teams in the continental competitions.
The top four Serie A teams get a spot in the Champions League at the group stage. The number 5 team can proceed to the UCL as well, because of the new rules established a few years ago which awards a league additional spot in the top tier of European football if it has best yearly UEFA coefficient.
If that doesn’t happen, the 5th place will lead to the Europa League qualifiers and the 6th to the Conference League qualifiers. Another UEL spot is guaranteed for the Coppa Italia winners.
Biggest Clubs in the Serie A
In the 21st century, only four teams have won the Scudetto, namely Juventus, Inter, AC Milan, and AS Roma. However, this wasn’t always the case – there are 12 other clubs that have won the title of the top Italian tier in the past.
Some of those teams (Napoli, Lazio, etc.) are still flying very high in Serie A, although the trophy seems to slip from their hands in the end. Then, there are some previous winners that are struggling to stay in the top tier, including Genoa and Bologna. And there are also past winners that no longer play professional football, such as Casale and Novese.
Let’s leave the past for the history books and focus on the future! So, which clubs are we going to see competing for the Scudetto in the 2026? Although nothing is certain in soccer, there is a handful of teams that stand out from the crowd in the Serie A, namely the following:
- Inter Milan – AC Milan’s city rival has seen some major improvements lately winning three of the past 6 Serie titles. They are the reigning champions, and are now among the biggest Serie A contenders.
- AS Roma – With the club hero Francesco Totti in the team, AS Roma managed to get ahold of the Scudetto at the beginning of the century. Since his retirement, the team from the Italian capital hasn’t been that successful, although we’ve seen a resurgence in the last couple of seasons.
- Juventus – With 36 titles in total, 11 of which that were won in this century, Juventus has been synonymous with success in Italian soccer. However, Juventus did have its share of shameful Serie A moments, most notably its involvement in the ‘Calciopoli’ scandal that got the club stripped off the Serie A title due to match-fixing.
- AC Milan – Although the Rossoneri haven’t been that great in the last couple of years, this team has a really impressive history. Not only did AC Milan win 19 Serie A trophies, but this side has also won dozens of continental trophies. For instance, during the Berlusconi-era, the club has won 5 Champions League titles.
- Napoli – The Sky Blues form Naples won the Serie A when the legendary Diego Maradona was in the team. Those years are still remembered as the golden era in this city. But, then some rough times hit the club, culminating in bankruptcy. Famous Italian film producer Aurelio De Laurentiis then came as the savior of the club, eventually making it a serious candidate for winning the Serie A. Btw, Napoli took the title in 2023 and 2025.
- Lazio – Despite not being considered the best team in Italy, Lazio has always been near the top of the table. And in a recent couple of seasons, the squad of Lazio has been packed with super-talented players.
Serie A Records and Milestones
- The year 1898 is generally considered to be the year when Serie A was born. That’s when the Campionato Italiano di Football was founded, which is the predecessor of the competition we know today.
- The first-ever winner of the Italian championship was Genoa, a team that then went on winning eight other titles, ending with the one from the 1923–24 season.
- With nine titles in total, Genoa is the fourth-most successful club in the Serie A. AC Milan with 19 and its city-rival Inter with 21 titles are above on the list. Still, the team with the most titles is Juventus with 36.
- Serie A clubs have been very successful on the continental stage as well, winning a total of 12 Champions League trophies (including those from the times when the competition was called the European Cup).
- When it comes to players’ milestones, the player with the most goals scored in Serie A is Silvio Piola with 274 goals to his name. It’s very unlikely that someone is going to surpass that number anytime soon as there are no active players with over 200 goals scored in this league.
- Gunnar Nordahl holds the record for most Capocannoniere titles. This award that literally translates to as the ‘head gunner’ is given to the most-prolific goalscorer at the end of every season.
- There are no players who can break Nordahl’s record of five Capocannoniere awards. At least not this season, although
Serie A Betting Tips
When it comes to betting on Serie A events, an important thing to remember is that the home turf matters a lot in this league.
Italian soccer stadiums are huge, with the biggest one, Stadio Giuseppe Meazza, having the capacity of over 80,000 seats. With so many fans supporting the home side, the host often performs better than expected.
But, it’s just about the size of the stadium. Some Italian clubs, such as Napoli, have incredibly passionate fans, who have the power to lift their team’s spirit when needed.
Another good piece of advice is to focus on the team’s style of play. There are some Italian teams that are great at the back, while others feel most comfortable when they are attacking.
For instance, Juventus has been famous for their defensive wall that’s almost unbreakable, with Giorgio Chiellini and Leonardo Bonucci playing as central defenders. Recently, with the appointment of Antonio Conte as the manager, a similar has become the case with Inter.
On the other hand, there are some attacking-minded teams like Atalanta or Lazio, which usually score over two goals per game on average.
