MLB: Giants vs Padres Odds, and Picks (Apr 29)

By · April 28, 2023
  • The Giants were shut out, 6-0, against the Cardinals.
  • San Diego fell to the Cubs, losing by a score of 5-2.
  • San Francisco is 483-436 in their all-time history against the Padres.

San Francisco (11-14) and San Diego (13-14) meet for an intriguing NL West rivalry series. Both teams are close to 1st place in a bad division, and will be aiming to climb the standings during this Mexico City series.

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How to Watch

  • Where: Estadio Alfredo Harp Helú, Mexico City, MX
  • When: Saturday, April 29, 2023, at 6:05 p.m ET
  • How to Watch: NBC Sports



Game Preview

San Francisco had their 5-game winning streak snapped on Thursday, falling to 11-14 on the season. They still remain just 2.5 games out of 1st place in the NL West, thanks to no single team doing exceptionally well in that division. The Giants regressed last season after winning over 100 games in 2021, and started this season very slow as well. They’ll be aiming to build on their recent winning ways in this rivalry series.

The Padres fell to below .500 with their loss to the Cubs. They sit 1.5 games out of 1st in the NL West, but have gone 6-9 over their last 15 games. In their last 7 losses, they were outscored 42-5. However, they’ve also played one of the MLB’s toughest schedules, with 22 out of 27 games coming against a team ranked 1st or 2nd in their division. The Padres will get a break against the 4th-place Giants, needing to capitalize.


This is a game that could very well go either way. San Diego is currently just 1 game ahead of San Francisco, and neither team has home-field advantage in an international game in Mexico City. Both starting pitchers have struggled this season, but Joe Musgrave (5.40 ERA) of the Padres has been marginally better than Sean Manaea (6.61 ERA) of the Giants. I trust San Diego’s offense more too.

MLB Picks:

Keith McCarthy
Contributor Keith McCarthy is an experienced sports analyst with a passion for predicting the outcomes of games spanning across sports such as football, basketball, baseball, and hockey, with a special expertise in college sports.