MLB: Giants vs White Sox Odds, and Picks (Apr 5)

By · Updated 1 year ago
  • The Giants crushed the White Sox on Monday, earning a 12-3 victory.
  • Chicago gave up 6+ runs for the 4th straight game, losing once again.
  • The White Sox are 16-7 in their all-time history against the Giants.

The San Francisco Giants and the Chicago White Sox match up for a key game 2 in this series. Both teams are hanging around the .500 mark, and can completely change their early momentum based on this game.

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How to Watch

  • Where: Guaranteed Rate Field, Chicago, IL
  • When: Wednesday, April 5, 2023, at 2:10 p.m ET
  • How to Watch: Bally Sports


White Sox

Game Preview

San Francisco pummeled the White Sox on Monday, returning to .500 for the season. A 2-2 start in 4 road games against the Yankees and White Sox is not the worst situation for the Giants, who could build some additional momentum with a series win here. They got a great first start from Anthony DeSclafani, who pitched 6 shutout innings in the win. On offense, they hit 6 home runs, 4 of which came in the 5th inning.

The White Sox fell to 2-3 with their loss on Monday. It seems like an underwhelming start, but they claimed 2 of 4 games on the road against the defending champion Astros to start the season. If they can bounce back against the Giants in this game, they could still start the season strong. Chicago needs a better performance from their starting pitcher, after Michael Kopech allowed 7 runs in 4.2 IP on Monday.


After losing badly to the Giants on Monday, it may seem unlikely that the White Sox would win the next matchup. That being said, day-by-day performance varies wildly in baseball, especially early season. In the next game, Chicago has Dylan Cease on the mound, who pitched to a 2.20 ERA last season and gave up just 1 run in 6.1 IP against Houston. His ability should allow them to get the win and even out the series.

MLB Picks:

Keith McCarthy
Contributor Keith McCarthy is an experienced sports analyst with a passion for predicting the outcomes of games spanning across sports such as football, basketball, baseball, and hockey, with a special expertise in college sports.