Jacksonville Jaguars vs Buffalo Bills Odds, and Picks (Oct 8)

By ยท Updated 9 months ago
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  • Spread X.X
  • To Win XXX
  • Total X.XX
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  • Spread X.X
  • To Win XXX
  • Total X.XX
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  • Jacksonville easily defeated the Falcons, 23-7, in London on Sunday.
  • The Bills surged past the 3-0 Dolphins, winning by a score of 48-20.
  • These two teams last met on November 7, 2021, in a game the Jaguars won 9-6.

With the NFL season is in full swing, let’s preview the upcoming Jaguars vs Bills AFC matchup. Jacksonville remains in London for their 2nd game, aiming to go 2-0 overseas, while Buffalo seeks to build momentum.

How to Watch

  • NFL Network


The Jaguars improved to 5-5 all time in London, hoping to push that record back above .500 this week. Their defense was very impressive against Atlanta. LB Josh Allen had his 2nd 3-sack game of the season, and now holds a tie for 1st in the NFL in overall sacks. 2022 1st-overall pick Travon Walker was also active, picking up a sack of his own. If their offense starts to heat up, Jacksonville will have a shot to win the AFC.

Buffalo dominated Miami last week, winning the game 48-20. It was an especially impressive performance for the defense. They managed to cool down a blistering hot Dolphins offense, while keeping up their own hot offensive play. Since losing to the Jets in Week 1, the Bills have outscored their opposition 123-33. Unfortunately, they also lost star CB Tre White to an achilles injury, casting a shadow over their victory.


The Jaguars haven’t looked that great on offense yet this season, and face their toughest defensive test so far against Buffalo. That being said, they have a capable defense of their own and offensive assets that could break out at any time. The Bills showed they are susceptible to an upset in Week 1, but have looked really solid since then. I see this game being pretty close, but I’d ultimately take the Bills to win by a score.

NFL Picks:

  • Bills 26, Jaguars 20 ()
Keith McCarthy
Contributor Keith McCarthy is an experienced sports analyst with a passion for predicting the outcomes of games spanning across sports such as football, basketball, baseball, and hockey, with a special expertise in college sports.