La Liga: Espanyol vs. Real Madrid Preview, Odds, Predictions (Aug 22)

By · Updated 2 minutes ago
  • Espanyol vs. Real Madrid odds set Los Blancos as -210 favorite.
  • Jose Mourinho starts his second tenure at Real.
  • Espanyol won the season opener against Levante 3-0.

The Los Blancos start the campaign in Barcelona against Espanyol. They eye the title, but winning it requires a darn good effort this year.

Here are more soccer picks.

Game Preview

  • When: Saturday, August 22, 2026, 3:30 PM ET
  • Where: RCDE Stadium, Cornella de Llobregat, Madrid
  • How to Watch: ESPN, ESPN+, FUBO

Espanyol vs. Real Madrid Odds

TeamOdds
Espanyol+630
Tie+470
Real Madrid-210

Game Preview

Espanyol’s opening La Liga fixture went well. The team from Barca beat Levante 3-0, displaying a commanding performance on both ends of the field.

Roberto Fernandez Jaen netted a brace inside the first half, and that really decided this one. After that, Tyhrys Dolan sealed the win in the 80th minute of the game. Overall, this was a dream start for Espanyol.

Real opens the campaign with this event. Los Blancos didn’t play the first-round clash, so this one marks the start of the year for them.

Mourinho’s unit didn’t lose a single game during the preseason, winning 4 and recording a tie. The last test was against Schalke, which Los Blancos won, 0-3. Mbappe and Huijsen scored a goal apiece in the opening 20 minutes, knocking out the Germans.

Espanyol vs. Real Madrid Head to Head

Real was pretty much routine against Espanyol last year, winning 2-0 in both matches. They have 4 wins in the past 5 matches, while the Catalans have won once.

Espanyol vs. Real Madrid Predictions

Real wants to open the season with a statement, because this is a fresh start for them, with Mourinho in charge. We won’t chase big odds, however, but go with a safe pick, which is, in this case, Real’s plain triumph.

Nikola Velickovic
Contributor Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.

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