National League Division Series: Brewers vs. Padres Picks, Series Odds & Betting Analysis

By · Updated 6 hours ago
  • This is the first postseason meeting between the Brewers and Padres.
  • The Padres won the regular series between the teams 4-2.
  • San Diego overcame the Chicago Cubs in the Wild Card round.

The National League Division Series in the MLB gets underway between the Milwaukee Brewers and San Diego Padres on Oct 3, 2026. The best-of-five series will determine the team that will reach the National League Championship Series this season. You can find our series picks and the Brewers vs. Padres series odds here. 

Brewers vs. Padres Series Odds

Series ResultOdds
Brewers-180
Padres+150

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Brewers vs. Padres Series Overview

Brewers vs. PadresWhereWhenHow to Watch
Game 1American Family Field, MilwaukeeOctober 3, 2026. 8:30 PM ETNBC, Peacock
Game 2American Family Field, MilwaukeeOctober 4, 2026. 4:00 PM ETNBC, Peacock
Game 3Petco Park, San DiegoOctober 6, 2026. TBD ETNBC, Peacock
Game 4Petco Park, San DiegoOctober 7, 2026. TBD ETNBC, Peacock
Game 5American Family Field, MilwaukeeOctober 9, 2026. TBD ETNBC, Peacock

Milwaukee Brewers vs. San Diego Padres Series Preview

Brewers Targeting Second Straight Championship Game

The Milwaukee Brewers will be looking to rewrite history in 2026 after being whitewashed by the Los Angeles Dodgers in last season’s National League Division Championship game. However, the Brewers have been a reliable outfit in the postseason in recent years, making the playoffs in all but one of the last eight seasons.

The Brewers finished at the top of the National League Central division, making franchise history by winning 100 games for the first time. A reliable end to the season saw them go 8-1 at American Family Field, and 18-6 overall in September.

Padres Aiming to Reach First Championship Game Since 2022

The San Diego Padres upset the odds in the Wild Card round to eliminate the Chicago Cubs in two games. They should be respected in this series, having made the playoffs in five of the last seven seasons. However, the Padres haven’t made the Championship Game since 2022.

San Diego finished as runners-up in the NL West, achieving an overall record of 91-71. Their biggest strength was their home form, going 51-30, but enduring challenges on the road with a 40-41 losing record. Ty France and Jackson Merrill both scored runs in the Game 2 win over the Cubs.

Milwaukee Brewers vs. San Diego Padres MLB Series Picks

The Padres boasted an excellent record over the Brewers in the regular season, winning four of the six meetings. However, the Brewers are established in the postseason, and look like the major challenger to the Dodgers for the National League championship. Therefore, we foresee Milwaukee coming through in three.

Alex Dudley
Contributor Alex has covered huge sporting events for various websites and publications. He has attended football European Championships, Rugby League and Union World Cups, and the Paralympics. Alex is dedicated to giving the most insightful tips for VegasOdds readers and specialises in horse racing, soccer, golf and basketball.

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