MLS Picks Oct 31-Nov 1: Best Bets, Odds and Predictions for Every Match
Best pick: Columbus Crew to win vs D.C. United (-298)
Best BTTS pick: Charlotte vs Orlando City, Yes (-357)
Best over/under: LAFC vs Minnesota United, Over 3 goals (-121)
MLS parlay: Columbus, LAFC, Orlando City and Inter Miami to win (+1655)
Claim Up to $250 Free Bet at BetOnlineThe pressure is on in MLS this weekend, with just two weeks left in the regular season and playoff spots still up for grabs in both the Eastern and Western Conferences. Below you’ll find our MLS picks for every match, along with our best moneyline pick, best both teams to score bet, best over/under and a four-leg parlay.
MLS Picks: Key Match Breakdowns
Columbus Crew vs D.C. United Prediction & Odds
Kickoff: Saturday, Oct 31 · 2:00 PM ET · ScottsMiracle-Gro Field, Columbus
| Outcome | 3-Way Moneyline | Spread | Total |
|---|---|---|---|
| Columbus Crew | -298 | -1.5 (-111) | Over 3.5 (+100) |
| Draw | +470 | ||
| D.C. United | +695 | +1.5 (-113) | Under 3.5 (-130) |
This is a must-win game for the Columbus Crew, as a victory would keep them in the final wild card spot in the Eastern Conference. The good news is that the Crew is in red-hot form, with four straight wins, scoring at least twice in each of them, including a 2-0 road win over FC Dallas in midweek.
D.C. United is already out of playoff contention and has little but pride to play for. They’ve lost four in a row, conceded two or more goals in six of their last seven, and won just twice in 16 road matches this season. That makes a Columbus home win one of the best MLS bets this weekend.
At -298, the Crew is a short price, so if you want more of a payout, Columbus -1.5 at -111 is worth a look. With the Crew scoring two or more in four straight and D.C. conceding at least twice in six of seven, a two-goal win is very much in play.
- Best bet: Columbus Crew to win (-298)
Colorado Rapids vs Chicago Fire Prediction & Odds
Kickoff: Saturday, Oct 31 · 9:30 PM ET · DSG Park, Commerce City
| Outcome | 3-Way Moneyline | Spread | Total |
|---|---|---|---|
| Colorado Rapids | +119 | -0.5 (+119) | Over 3 (+100) |
| Draw | +272 | ||
| Chicago Fire | +209 | +0.5 (-156) | Under 3 (-130) |
This one has big playoff implications in both conferences. The Chicago Fire clinched a postseason spot in midweek with an entertaining 2-2 draw against Orlando City, but they’ll need to tighten up at the back to go on a deep run, having allowed five goals in their last three.
The pressure is all on the Rapids. Colorado sits seventh in the Western Conference, and a loss could drop them outside the top nine heading into the final weekend of the regular season. They’re unbeaten in five, but have won just once in that stretch, with four of those matches ending in draws.
With Colorado drawing four of its last five and Chicago already safe, a share of the points looks likely, and at +272, the draw is the value play in this one.
- Best bet: Draw (+272)
MLS Picks for Every Match This Weekend
| Kickoff (ET) | Match | Prediction | Odds |
|---|---|---|---|
| Sat 1:00 PM | Charlotte FC vs Orlando City | Orlando City | +250 |
| Sat 2:00 PM | Columbus Crew vs D.C. United | Columbus Crew | -298 |
| Sat 2:00 PM | FC Cincinnati vs Philadelphia Union | Both teams to score | -333 |
| Sat 2:00 PM | New York City FC vs CF Montreal | New York City FC | -245 |
| Sat 3:00 PM | Sporting KC vs FC Dallas | FC Dallas | -125 |
| Sat 3:00 PM | St. Louis City vs San Diego FC | St. Louis City | -119 |
| Sat 5:00 PM | LA Galaxy vs Austin FC | LA Galaxy | -215 |
| Sat 5:00 PM | San Jose Earthquakes vs Real Salt Lake | Both teams to score | -222 |
| Sat 9:30 PM | Colorado Rapids vs Chicago Fire | Draw | +272 |
| Sun 3:30 PM | Vancouver Whitecaps vs Seattle Sounders | Vancouver Whitecaps | -162 |
| Sun 4:30 PM | Atlanta United vs Toronto FC | Over 3.5 goals | +106 |
| Sun 4:30 PM | Nashville SC vs New York Red Bulls | Nashville SC | -202 |
| Sun 7:00 PM | New England Revolution vs Inter Miami | Inter Miami | +127 |
| Sun 8:30 PM | LAFC vs Minnesota United | LAFC | -153 |
| Sun 9:45 PM | Portland Timbers vs Houston Dynamo | Portland Timbers | -128 |
Odds via BetOnline. “To win” picks are 3-way moneylines, so a draw loses.
MLS Parlay Picks This Weekend
Our best MLS parlay this weekend mixes two home favorites with two road teams at plus money: Columbus Crew, LAFC, Orlando City and Inter Miami to win. On BetOnline, that four-leg parlay pays around +1655, so a $100 bet returns $1,755.
It’s a long shot, with Orlando at +250 and Inter Miami at +127 both needing road wins, but that’s what drives the big payout. If you’d prefer a safer two-leg parlay, Columbus and LAFC together pay a much shorter price, and both are at home. Remember that every leg needs a win in 90 minutes, as a draw in any match means the parlay loses.
| Parlay | Legs | Odds | $100 returns |
|---|---|---|---|
| MLS four-leg parlay | Columbus, LAFC, Orlando City, Inter Miami | +1655 | $1,755 |
| Safer two-leg parlay | Columbus, LAFC | +188 | $288 |
Where to Bet on MLS This Weekend
All of these sportsbooks accept US players and offer MLS moneylines, spreads, totals and both teams to score markets, plus a welcome bonus for new players.






