NFL Odds, Predictions: Panthers vs. Falcons Week 2 Preview & Picks (Sep 20)

By · Updated 25 minutes ago
  • Panthers vs. Falcons odds favor Carolina at
  • Cooper Rush will start if both Tua and Penix Jr. are injured.
  • Panthers lost to Bears in a highest-scoring opener ever, 59-37.

Both of these NFC South teams lost their opening games. Coming into this one, the Panthers are favorites; however, the Falcons looked solid in Pittsburgh, despite starting with third-string quarterback Cooper Rush.

Check for more NFL odds and picks here.

How to Watch

  • When: Sunday, September 20, 2026, 1 PM ET
  • Where: Mercedes-Benz Stadium, Atlanta, Georgia
  • How to Watch: FOX

Panthers vs. Falcons Odds

TeamMoneylineSpreadTotals
Panthers-125-1.544.5
Falcons+105+1.544.5

Game Preview

Panthers lost to the Chicago Bears in Week 1, 59-37. The defense looked terrible, and Caleb Williams cut through it like a knife through butter. This was the highest-scoring opening game ever, and it resulted in a Scorigami. The defense allowed 247 rushing yards and 552 total yards.

QB Bryce Young threw for 361 passing yards and 3 touchdowns with an interception. Jalen Coker had 138 receiving yards with two TDs.

Falcons could have defeated the Steelers in Pittsburgh, as they had their chances. In the end, it was 20-13 for the hosts, who squeezed this one out. Now, when we say that Atlanta did this with Cooper Rush as the starter, the whole situation sounds much better.

The No.3 QB had only 143 passing yards with a TD and two picks. Tua and Penix Jr. are still questionable, yet if one of them steps up this Saturday, the Falcons should look way better. Also, RB Bijan Robinson had 173 yards from scrimmage and a TD.

Panthers vs. Falcons Predictions

This one is all about who starts for the Falcons. If either of the two mentioned (Tua or Penix) begins in the backfield, we are picking the Falcons to win. With either of those, this team is at least 30% better than with Rush.

Nikola Velickovic
Contributor Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.

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