NFL Odds, Predictions: Steelers vs. Patriots Week 2 Preview & Picks (Sep 20)

By · Updated 3 minutes ago
  • Steelers vs. Patriots odds favor New England by 5.5 points.
  • Patriots lost to the Seahawks 13-10 on opening night.
  • The Steelers defeated the Falcons 20-13 in Week 1.

Once, this was an AFC classic. Back when Big Ben and Tom Brady ran the NFL, we often saw these two franchises clash in the playoffs. Now, things are different, but the hype is still the same.

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How to Watch

  • When: Sunday, September 20, 2026, 1 PM ET
  • Where: Gillette Stadium, Foxborough, Massachusetts
  • How to Watch: CBS

Steelers vs. Patriots Odds

TeamMoneylineSpreadTotals
Steelers+170+4.543.5
Patriots-205-4.543.5

Game Preview

TJ Watt had two sacks against the Falcons. He was fantastic, along with LB Payton Wilson, who posted 13 tackles. The defense was the main reason why the Steelers won this one. And the fact that the Falcons started with third-string QB Cooper Rush.

Aaron Rodgers threw 40 times and completed only 24 passes. He tossed for 221 yards and one touchdown. He would probably be better if his running backs provided more than 61 rushing yards.

The Patriots lost once again to the Seahawks, only this time in the regular season. It was 13-10 at Lumen in Week 1, and even though the Pats played against Sam Darnold-less Seattle, they couldn’t beat the champs.

Why? The reason is simple: Drake Maye. He was picked three times, having just one TD pass and a QBR of 58.5. Maye suffered three sacks, and the Patriots will need more time to better sync Maye’s protection.

Steelers vs. Patriots Predictions

Defenses will lead the way here. It’s no wonder the total is set at 42.5 points. Pittsburgh has problems with its run game, Patriots have problems protecting Maye, so under is our choice here.

Nikola Velickovic
Contributor Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.

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