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NFL Week 1: Cardinals vs. Saints Preview, Odds, Picks (Sep 7)

By · Updated 7 hours ago
  • Cardinals vs. Saints odds favor Arizona by 6.5 points.
  • Spencer Rattler has been named as the New Orleans Saints’ starting QB.
  • The total for this game is 42.5 points.

The Arizona Cardinals looked strong during the preseason, and they have high expectations for this season. Meanwhile, the Saints didn’t win a single game during the preseason and now want to redeem themselves.

If you are interested in more NFL odds and predictions, follow this link.

How to Watch

  • When: Sunday, September 7, 1 pm ET
  • Where: Caesars Superdome, New Orleans, Louisiana
  • How to Watch: CBS

Cardinals vs. Saints Odds

TeamMoneylineSpreadTotals
Cardinals-280-6.542.5
Saints+230+6.546.5

Game Preview

The Arizona Cardinals just missed the playoffs last year, but it seems they have the quality to reach the postseason this season. Kyler Murray should have one standout season and prove his worth. After all, he got more than $230 million from the Cards.

Cards defense is significantly better than before. DE Dalvin Tomilson is here, DT Walter Nolen was the 16th pick overall, CB Will Johnson was the second-rounder, etc. So overall, Arizona has a decent team with solid experience.

The Saints, according to many, are one of the worst teams in the NFL. And that’s because they don’t have a QB. Their No. 1 quarterback will be Spencer Rattler, who started seven games last year and lost all of them, completing four touchdown passes and throwing five interceptions.

On the defensive side, things are much better, particularly after Justin Reid came from the Chiefs. DE Cameron Jordan is there, as is LB Chase Young, so they will have some influence in that aspect of the game.

Cardinals vs. Saints Head to Head

There have been 32 games between these two franchises, and the current record is tied, with 16 wins apiece.

Arizona won the previous meeting in 2022, 42-34, in Glendale.

Cardinals vs. Saints Predictions

Arizona looks better, and we believe the guests will have a fairly easy win in this event.

Nikola Velickovic
Contributor Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.

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