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NFL Week 12: Indianapolis Colts vs. Kansas City Chiefs Preview, Odds, Picks (Nov 23)

By · Updated 1 day ago
  • Colts vs. Chiefs odds favor Kansas City by 3.5 points.
  • The Kansas City Chiefs have back-to-back defeats.
  • Indianapolis Colts are the No.1 offense in the NFL, 32.1 points per game.

While the Colts chase the AFC No.1 seed, the Chiefs are fighting for the playoffs right now. And a loss here would be a big setback for Mahomes and the guys.

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How to Watch

  • When: Sunday, November 23, 1 pm ET
  • Where: Arrowhead, Kansas City, Missouri
  • How to Watch: CBS

Colts vs. Chiefs Odds

TeamMoneylineSpreadTotals
Colts+150+3.550.5
Chiefs-175-3.550.5

Game Preview

The Indianapolis Colts lost to the Steelers three weeks ago, but then beat the Falcons, 31-25, in overtime the following Sunday. This game was in Berlin, by the way. Daniel Jones and the boys didn’t play well, but in the end, they posted win number 8 of the current campaign. After that, Indianapolis had a week off.

Believe it or not, Jonathan Taylor ran 244 yards back then, scoring three touchdowns. He delivered pure art at the Olympic Stadium, showing the best the NFL has to offer to European fans. Taylor already has 1,139 rushing yards this year.

The Chiefs’ first of back-to-back failures was against the Bills, 28-21, followed by a tough loss to the Broncos, 22-19. Both games were on the road. The painful thing about the defeat to Denver is that it came from a division rival who already has a significant advantage in the standings. Plus, it was a last-second FG.

Rushers had just 62 yards, while Mahomes threw for 276 yards, one TD, and a pick. The team no longer has a stable offense, while the defense continues to perform solidly, allowing 18.4 points per game.

Colts vs. Chiefs Head to Head

In 28 games, the Colts have 18 wins, the Chiefs 10. Indianapolis won the last two, the previous being in 2022, 20-17 at home.

Colts vs. Chiefs Predictions

If Jonathan Taylor does not play at his usual level, the Chiefs will win. And overall, our pick, even with JT’s good game, is the hosts, because Kansas City returns to the Arrowhead, and Daniel Jones isn’t that convincing these days. When you combine these two factors with the Chiefs’ experience, our suggestion becomes logical.

Nikola Velickovic
Contributor Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.