NFL Week 13: Packers vs. Lions Preview, Odds, Picks (Nov 27)

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NFL Week 13: Green Bay Packers vs. Detroit Lions Preview, Odds, Picks (Nov 27)

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Packers vs. Lions preview, odds, prediction for the November 27 NFL Week 13 at Ford Field on Thanksgiving Day.

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Packers vs. Lions open the NFL Thanksgiving Day program.
Green Bay beat the Lions in Week 1, 27-13.
Lions are the favorites according to the NFL odds at -140.

The battle for the No.1 seed in the NFC North takes us to Detroit, where the Lions host the Packers on Thanksgiving Day.

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How to Watch

When: Thursday, November 27, 1 pm ET
Where: Ford Field, Detroit, Michigan
How to Watch: FOX

Packers vs. Lions Odds

Team	Moneyline	Spread	Totals
Packers	+120	+2.5	49.5
Lions	-140	-2.5	49.5

Game Preview

The Packers have a slight edge in the standings, yet they can’t afford to lose to the Lions in order to keep the top spot in the NFC North. They are coming off a win against other division rivals, the Vikings, 23-6, flying high on morale.

Green Bay’s defense is elite, and allows only 18.4 points per game. Right now, they are the 4th overall in allowed yards per game with 278.7. Micah Parsons has 10 sacks so far, while Rashan Gary recorded 7.5

Micah Parsons leads the NFL with 57 pressures, including 8 sacks, despite facing a double-team at the 2nd-highest rate among edge defenders with at least 150 pass rushes this season (21.6%) pic.twitter.com/7xiaoTM4V5
— Underdog Fantasy – Josh & Hayden (@UDFootballShow) November 24, 2025

The Lions squeezed out a win over the Giants at home, 34-27 OT. This wasn’t Detroit’s win, but the guests’ loss, and to be honest, the Lions fans weren’t thrilled too much after the game.

Jarred Goff leads the second offense in the league with 29.6 points per game. Though we need to say that, as time goes by, we are starting to believe the true leader of this unit is running back Jahmyr Gibbs, who has 951 rushing yards this season and 10 touchdowns. With 219 yards, he was the primary reason why the Lions beat the Giants.

Packers vs. Lions Head to Head

These two franchises met 192 times, and the Packers lead the series, 107-78-7. As stated, they beat the Lions in Week 1, 27-13.

Packers vs. Lions Predictions

The Packers’ defense is accelerating as the season progresses, and we believe they are going to show up here. Meanwhile, the Lions’ offense is statistically 2nd in the NFL, but it’s been quite volatile lately. As is, Jordan Love. That’s why our pick is under 49.5 points.

Free NFL Picks: Under 49.5 points

Nikola Velickovic Contributor

Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.