NFL Week 17: Detroit Lions vs. Minnesota Vikings Preview, Odds, Picks (Dec 25)

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NFL Week 17: Detroit Lions vs. Minnesota Vikings Preview, Odds, Picks (Dec 25)

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Lions vs. Vikings Week 15 Preview, Odds, Prediction for the game set at the US Bank Stadium on December 25.

https://commons.wikimedia.org/wiki/File:US_Bank_Stadium_-_49138374513.jpg

Lions vs. Vikings odds favor Detroit at -265.
The Minnesota Vikings have three wins in a row.
TOTAL went OVER in Detroit’s last 5 games.

The Lions are in the playoff hunt, yet they have to beat the in-form Vikes on the road. If Minnesota played like this the entire year, things would be much different in the NFC North.

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How to Watch

When: Thursday, December 25, 4:30 pm ET
Where: US Bank Stadium, Minneapolis, Minnesota
How to Watch: Netflix

Lions vs. Vikings Odds

Team	Moneyline	Spread	Totals
Lions	-265	-6	44.5
Vikings	+215	+6	44.5

Game Preview

The Lions lost three of their past four matches and went from division leaders to battling for the last playoff spot in the NFC. Their matches are efficient, and the previous 5 all ended with OVER, but Jared Goff and the boys are usually on the losing side after the end.

Losing to the Pittsburgh Steelers, 29-24, was after a wild ending in which Goff’s touchdown on the final play was canceled by Amon-Ra St. Brown’s offensive pass interference.

I'm convinced Justin Jefferson is the best teammate of all time.

Never any dram, going through the worst stretch of his career, and he's still supporting his teammates like crazy.

One of the GOATs for sure 👑 pic.twitter.com/ry5dLcppNv
— Cam (@42Cyc) December 19, 2025

As for the Vikes, they play tougher football, and just one of their last 7 matches saw OVER. The most recent victory was against the Giants, 16-13 in New York. Previously, they’ve beaten the Commanders at home, 31-0, and the Cowboys, also on the road, 34-26.

During this victorious stretch, JJ McCarthy had 5 touchdown passes, two intercepted throws, but also two rushing scores. One of them was in New York, where it made a crucial difference.

Lions vs. Vikings Head to Head

After 128 matches, the series record is heavily in Minnesota’s favor: Minnesota has won 81 times, the Lions 45, and 2 games have ended in a tie. This season, the Lions won 27-24 at home. It was the first triumph for Detroit after 5 losses in a row.

Lions vs. Vikings Predictions

It seems McCarthy has found some offensive rhythm, so this game should go OVER. The total line is set at 44.5 points, and we definitely pick OVER, as the Lions have no other way to win here but through offense.

Free NFL Picks: Over 44.5 points

Nikola Velickovic Contributor

Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.