Newcastle vs. Liverpool Picks, Odds, and EPL Betting Analysis — Magpie Misery to Continue as Reds Favored at -111
- When: Sunday, August 23, 2026. 11:30 AM ET
- Where: St. James’ Park, Newcastle, England
- How to Watch: NBC
Newcastle vs. Liverpool EPL Preview
One of the most historic rivalries in English top-flight history kicks off the 2026-27 Premier League season at St. James’ Park on August 23. Liverpool will be heavily fancied at the best soccer betting sites to make a winning start to the campaign against Newcastle, but could a potential shock outcome be on the cards in the North East of England?
ALSO SEE: Premier League 2026/27: Our Experts Make Their Winner, Relegation, and Top Scorer Picks
Magpies In Disarray Following Howe’s Departure
A challenging summer sees Newcastle come into the new campaign with plenty of questions to answer. The departure of Eddie Howe during pre-season saw Newcastle’s odds to suffer relegation crash, and the appointment of the largely inexperienced Matthias Jaissle has done little to raise confidence levels.
Key first-team players such as Bruno Guimaraes, Sandro Tonali, and Anthony Gordon have all departed this summer, and Newcastle have fallen short in their bids to bring top targets to the club. Instead, they have turned their attention to younger stars, with big money spent on players such as Bazoumana Toure, Lukas Hornicek, and Amar Dedic.
Pre-season results have done little to raise excitement levels, as Newcastle have lost three of their previous five.
Likely Lineup:
(4-3-3) Hornicek (GK); Dedic, Botman, Burn, Hall; Steur, Bamba, Joelinton; Toure, Wissa, Barnes
Reds Looking Ahead With Eyes on Youthful Stars
A major summer of change at Anfield brings with it fresh excitement for the new season. Arne Slot was removed as manager at the conclusion of the previous campaign, with Andoni Iraola tasked with getting Liverpool back to the top of the English game.
Mohamed Salah ended his association with the club at the end of last term, and the Reds are yet to replace the Egyptian superstar despite being heavily linked with PSG’s Bradley Barcola. Ibrahim Konate also departed the club, but he has been effectively replaced by talented young French defender Jeremy Jacquet, who will partner Virgil van Dijk this term.
Huge focus will be on Florian Wirtz and Alexander Isak after poor first seasons with the club after big-money moves. The latter will get a hostile reception on his return to St. James’ Park. It could be a big season for Rio Ngumoha, with the 17-year-old scoring twice in 19 EPL appearances last season.
Likely Lineup:
(4-2-3-1) Alisson (GK); Frimpong; van Dijk, Jacquet, Kerkez; Szoboszlai, Gravenberch; Ngumoha, Wirtz, Chiesa; Isak
Head-to-Head Stats
- Liverpool are unbeaten in their last 19 EPL fixtures against Newcastle United.
- The Reds have won four of their last five fixtures at St. James’ Park against the Magpies.
- Newcastle’s only competitive win against Liverpool in the last ten was achieved in the 2025 EFL Cup final.
Newcastle vs. Liverpool EPL Picks
There are already dark clouds gathering around St. James’ Park, and the mood could worsen this weekend following the visit of Liverpool. The Reds should have the attacking quality to run out convincing winners, and the head-to-head trends support their chances of victory over Newcastle.
