NHL Picks and Parlays: Best Bets For All Games on Oct 22, 2026

By · Updated 5 minutes ago

A busy evening of NHL action is set for Oct 22, as 12 games are slated across the Eastern and Western Conferences. We will be aiming to maintain our reliable strike-rate following a winning Best Bet selection on Oct 20. You can find our standout selection, a value play, and a team to fade on Thursday below. Meanwhile, NHL picks and parlays for all games will be provided at the bottom of the page.

NHL Picks and Parlays: Best Bets Today & Top Value Picks

  • Best Pick: Boston Bruins (vs. Nashville Predators)
  • Best Value: Ottawa Senators (-1.5) (vs. San Jose Sharks)
  • Team to Fade: Florida Panthers (@ Pittsburgh Penguins)
  • Best NHL Parlay Bet: Boston Bruins, Ottawa Senators, Pittsburgh Penguins All to Win & NY Rangers @ Toronto Maple Leafs (Over 6.0 Goals)

ALSO SEE: Breeders’ Cup Classic Picks, Odds, Leading Contenders, Betting Insights & Analysis


NHL Best Bets Today: Key Game Breakdown & Predictions

Nashville Predators @ Boston Bruins Prediction & Odds

Date: Thursday, October 22 | 7:00 PM ET | TD Garden, Boston  

Game Preview

The Nashville Predators snapped a three-game losing run in their latest outing, recording a 5-2 home win over the St. Louis Blues. However, their weak record on the road is worth considering this week, as the Preds have won just once in three.

The Boston Bruins have been very reliable in the opening months of the season, going 7-2-0 in the opening stretch. Jeremy Swayman has been a standout performer in the Boston goal, sporting an excellent 1.85 GAA. Boston’s recent form has also been red-hot, winning five of their previous six. Therefore, the home win ranks among the standout plays when making NHL picks and parlays on Thursday.

San Jose Sharks @ Ottawa Senators Prediction & Odds

Date: Thursday, October 22 | 7:00 PM ET | Canadian Tire Centre, Ottawa 

Game Preview

The San Jose Sharks have made a reliable start in the Pacific Division this season, as they sit fourth in the standings after going 5-4-1. Confidence would have been gained following a dramatic overtime win at the Montreal Canadiens on Tuesday evening. However, the Ottawa Senators could be the logical play when considering a value angle.

The Senators have won four of their previous six, but the main concern this week is that they will be playing on back-to-back nights. But, the poor defensive record of the Sharks ensures that the offensive fluency of the Senators should sparkle on Thursday.


Best NHL Bets For Every Game on Oct 22, 2026

NHL GameNHL Pick
New York Rangers @ Toronto Maple LeafsOver 6.0 Goals
Anaheim Ducks @ New Jersey DevilsNew Jersey Devils
Florida Panthers @ Pittsburgh PenguinsPittsburgh Penguins
Los Angeles Kings @ NY IslandersUnder 5.5 Goals
Vegas Golden Knights @ St. Louis BluesVegas Golden Knights
Winnipeg Jets @ Dallas StarsDallas Stars
Minnesota Wild @ Calgary FlamesUnder 6.0 Goals
Carolina Hurricanes @ Edmonton OilersOver 6.5 Goals
Utah Mammoth @ Seattle KrakenSeattle Kraken
Detroit Red Wings @ Vancouver CanucksVancouver Canucks

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Alex Dudley
Contributor Alex has covered huge sporting events for various websites and publications. He has attended football European Championships, Rugby League and Union World Cups, and the Paralympics. Alex is dedicated to giving the most insightful tips for VegasOdds readers and specialises in horse racing, soccer, golf and basketball.