NFL Week 1: Broncos vs. Chiefs Preview, Odds, Predictions (Sep 14)

By · Updated 27 minutes ago
  • Broncos vs. Chiefs odds favor Kansas City at -130.
  • Patrick Mahomes is back following his season-ending ACL injury.
  • Bo Nix and the Broncos won the AFC West last year.

Mahomes is back, and the Chiefs want their throne back. The best way to take the first step toward that goal is to beat last year’s AFC West champs, the Denver Broncos.

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Game Preview

  • When: Monday, September 14, 2026, 8:15 PM ET
  • Where: Arrowhead Stadium, Kansas City, Missouri
  • How to Watch: ESPN, ABC

Broncos vs. Chiefs Odds

TeamMoneylineSpreadTotals
Broncos+130+343.5
Chiefs-155-343.5

Game Preview

With Patrick Mahomes healthy, the Chiefs are among the Super Bowl contenders once again. According to NFL Comeback Player of the Year odds, Mahomes is the top favorite to win this award, and if his Chiefs win the division, we are sure that the former MVP will add one more trophy to his collection.

Kansas City boosted its backfield with RB Kenneth Walker III, who landed following a Super Bowl win. The defense is rejuvenated with two draft picks, CB Mansoor Delane and DT Peter Woods. There are several more additions to that part of the team, and we can’t wait to see how they fit in.

Sean Payton and Bo Nix are now the guys to beat. And do know that the entire league will be after the Broncos following last year’s AFC Championship Game. Nix got a fantastic target after the Broncos traded for WR Jaylen Waddle, who will be a huge addition to the offense.

Regarding the defense, Denver had one of the best, if not the best, in the NFL last year. Broncos recorded 68 sacks, the most in the league, and were fantastic when it came to pass rush. After all, that’s the main reason why this team reached so deep in the playoffs.

Broncos vs. Chiefs Head to Head

This rivalry has seen 132 games. Chiefs lead the all-time series, 73-59. However, the Broncos won the last three games.

Broncos vs. Chiefs Predictions

It appears that the Chiefs had a busier offseason, so they might need a bit more time to click. Plus, Mahomes is a bit rusty and unsure of himself, so we have to side with the Broncos here, who are the underdogs. We will pick them to defend the spread.

Nikola Velickovic
Contributor Nikola is one of those rare fanatics who dedicated their lives to sports. In the last five years, he has worked as a betting tips writer for several companies. Also, he does coverage of various sports events, and besides his betting skills, he is a sports news contributor on multiple websites. Here at VegasOdds, Nikola is in charge of the NBA, Champions League and the world’s most famous soccer competition the English Premier League.

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