NFL Odds, Predictions: Lions vs Cardinals Week 5 Preview & Picks (Oct 11)

By · Updated 17 minutes ago
Loading... Loading...
  • Spread X.X
  • To Win XXX
  • Total X.X
Loading... Loading...
Loading... Loading...
  • Spread X.X
  • To Win XXX
  • Total X.X
Loading... Loading...
  • The Lions came up short against the Panthers, losing 32-26 on the road.
  • Arizona was unable to hold off the battered Giants, falling to them 36-24.
  • These teams last met on September 22, 2024, in a game that the Lions won 20-13.
  • Detroit Lions -4.5

In this week’s Lions vs Cardinals matchup, two NFC teams battle to get a leg up in the standings. Detroit is slightly favored to win, despite being on the road, as they seek to earn their first win of the year away from home. Arizona will put them to the test in this one.

Lions Seek Bounce Back Road Win

The Lions dropped to 2-2 last week after losing to the Panthers. They remain in contention in the early going, but now find themselves two games behind the 4-0 Vikings in the NFC North. Detroit is 2-0 at home, but 0-2 on the road, facing another road test in this game against the Cardinals. This should be a winnable game to get into the win column away from home, but they’ll need to avoid another late-game collapse.

Cardinals in Need of a Victory

The Cardinals fell to 1-3 last week after failing to fend off Jameis Winston and the Giants. Arizona has now lost three games in a row since winning the opener against the now 0-4 Chargers. It’s been a string of losings seasons that just keeps growing longer and longer and the Cardinals find themselves in a tough spot. Despite QB Jacoby Brissett exceeding expectations, Arizona’s defense has heavily held them back.

9.8
No Strings Welcome Offer 50% up to $250 Gambling problem? CALL 1-800-GAME
9.8
Welcome Bonus 125% up to $2500 Gambling problem? CALL 1-800-GAME
9.6
Welcome Bonus 125% Free + 50 Free Spins Gambling problem? CALL 1-800-GAME

Lions vs Cardinals NFL Pick

Detroit may be on the road for this game, but they hold a notable advantage in skill over the Cardinals. They won’t finish the year winless on the road, so expect that streak to end sooner rather than later. Arizona’s loss to the Giants illustrated some major holes that the Lions are very likely to exploit. They should win this one by more than enough to cover the spread.

Keith McCarthy
Contributor Keith McCarthy is an experienced sports analyst with a passion for predicting the outcomes of games spanning across sports such as football, basketball, baseball, and hockey, with a special expertise in college sports.

More Predictions