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Expert prediction

NCAA Second Round: Texas A&M vs Houston Preview, Odds, Predictions (March 21)

  • Richard Pereira
  • Mar 21, 2026 at 1:08 PM EDT

Pick rationale

Analysis & key factors

  • The Aggies stunned Saint Mary’s in the Round of 64.
  • The Cougars blew out Idaho in the first round.
  • This marks the 87th all-time matchup between the two programs.

The evening hours of the March 21 slate will have high quality basketball when the Texas A&M Aggies take on the Houston Cougars in the second round of the 2026 NCAA Tournament. The latter stands out as the solid favorite, presenting a remarkable duel to see who gets to the Sweet 16.

How to Watch

  • When: Saturday, March 21, 6:10 pm ET
  • Where: Paycom Center, Oklahoma City, Oklahoma
  • How to Watch: TNT

NCAA Matchup Odds & Lines

TeamOddsSpreadTotals
Texas A&M-105+10O 143
Houston-115-10U 143

Game Preview

The Aggies (22-11) clinched an At-Large bid to March Madness despite falling to Oklahoma in the second round of the SEC Tournament. Rashaun Agee led the squad with 22 points on 7-of-11 shooting from the field. He also grabbed a game-high nine rebounds and dished out three assists, registering his seventh 20-point game this year and third in the last five games. Meanwhile, Rubén Dominguez poured in 11 points while Ali Dibba added nine to go along with seven boards.

The Cougars (28-6) easily overwhelmed Idaho in the first round of March Madness, making their case as a national championship contender like last season. Kingston Flemings scored 18 points and Emanuel Sharp added 16 points to lead them to victory. On another note, Chris Cenac Jr. grabbed a career-high 18 rebounds for Houston, and five Cougars scored in double figures to rout the Vandals in the Round of 64.

Texas A&M vs Houston Head-to-Head

The two programs have had 86 meetings in their history, and the result is 54-32 for the Cougars. The most recent matchup was in March 2024 when Houston won 100-95 in that year’s NCAA Tournament.

Texas A&M vs Houston Predictions

The winner of this matchup will take on the victors between VCU and Illinois in the Sweet 16. Texas A&M exceeded expectations as he shut down Saint Mary’s attack in the first round. However, their quality on both sides of the ball will be put to the test as the Cougars seek to overwhelm them in many aspects. Our betting pick here is for the Cougars to cover a 10-point spread.

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