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Europa League: AC Milan vs. Benfica Preview, Odds, Picks (Sep 16)

  • Nikola Velickovic
  • Sep 14, 2026 at 3:43 AM EDT

Pick rationale

Analysis & key factors

  • AC Milan vs. Benfica odds favor Milan as slight favorites at +110.
  • Benfica has 7 wins in a row, scoring 25 goals during that run.
  • AC Milan has back-to-back ties, against Juve and Lazio.

Two former European champions meet in Milan in the Europa League clash. Both are favorites to win the competition, which is why all the attention is on San Siro.

Here are more Europa League picks and odds.

How to Watch

  • When: Wednesday, September 16, 2026, 3:00 PM ET
  • Where: San Siro, Milan, Italy
  • How to Watch: Paramount+

Europa League Odds

Match ResultOdds
AC Milan+110
Tie+240
Benfica+235

Game Preview

After opening wins, AC Milan posted two road ties. One was against Juventus, 1-1, and the second against Lazio at the Olimpico, 2-2. We saw Rossoneri coming back from a two-goal deficit, yet Christian Pulisic and the boys couldn’t deliver the final blow to Lazio.

We have to say that Pulisic’s entrance off the bench completely changed the picture against Lazio. The American superstar brought in the spark and was the best player on the pitch.

Benfica has 7 wins in a row, and overall 8 in the last 10 appearances. The remaining two were ties, so the Eagles are undefeated since early August. Now, what’s even more important to say is that the Portuguese powerhouse scored 25 goals during their victorious stretch.

The tip of their spear is the fantastic Greek international, Vangelis Pavlidis, who already has 14 goals on his tally so far. Also, the 20-year-old Argentinian, Ginaluca Prestianni, has 8, and the two are working superbly together.

AC Milan vs. Benfica Head to Head

Their last meeting was a club friendly in 2019, when Benfica won 1-0. They’ve also met twice in the Champions League finals, once in 1963 when Milan won 2-1 and in 1990, when Milan also triumphed 1-0.

AC Milan vs. Benfica Predictions

Both teams push hard in attack, so we predict a high-scoring game with at least three goals.

Free Europa League picks: Over 2.5 Goals

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