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Expert prediction

International Friendly: Mexico vs. Colombia Preview, Odds, Picks (Sep 26)

  • Nikola Velickovic
  • Sep 23, 2026 at 8:38 AM EDT

Pick rationale

Analysis & key factors

  • Mexico vs. Colombia odds are pick’em: +160 vs. +165.
  • Mexican football legend Rafael Márquez makes his official head coaching debut for the Sombreros.
  • The game takes place at the M&T Bank Stadium in Baltimore.

A Latin clash in Baltimore brings together Mexico and Colombia in their first meeting since the World Cup.

For those who want more betting picks, here is the USA vs. Peru preview.

How to Watch

  • When: Saturday, September 26, 2026, 9:00 PM ET
  • Where: M&T Bank Stadium, Baltimore, Maryland
  • How to Watch: Univision / TUDN / Fox Sports

Mexico vs. Colombia Odds

Match ResultOdds
Mexico+160
Tie+250
Colombia+165

Match Preview

Rafa Marquez takes the hot seat as the new head coach of the Mexican national team. The most decorated player in this country ever is under huge pressure to deliver notable results in the future. That’s why many are eager to see his debut against Colombia.

Without the legendary Raul Jimenez, Mexico’s attack will rely on Hirving Lozano and Santiago Gimenez. During the World Cup, Sompreros scored twice in 4 of 5 games and kept a clean sheet in each, except the Round of 16 against England, 2-3.

UEFA Nations League Matchday 1 Predictions: Best Bets & Picks (Sep 24-26)

Colombia is at a crossroads. They will need new stars and new tactics, because many of their leading players are veterans well past their peak. Some, like Rodriguez, have retired. That’s why Nestor Lorenzo called up plenty of youngsters and new names.

Bayern Munich’s Luis Diaz is out, so Davison Sanchez and Jhon Arias will lead the unit. Just to add, there are 11 debutants on the roster.

Mexico vs. Colombia Head to Head

The last time these two sides met was in October 2025, and Colombia rolled over Mexico, beating them 4-0 in the friendly international. In 2023, they won 3-2, the same as one year earlier.

Mexico vs. Colombia Predictions

Both coaches will combine a lot here and try to get a glimpse of new players, tactics, strategies, etc. That’s why we expect goals on both ends.

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