Skip to content

Expert prediction

La Liga: Atletico Madrid vs. Real Madrid Preview, Odds, Picks (Sep 20)

  • Nikola Velickovic
  • Sep 17, 2026 at 5:17 AM EDT

Pick rationale

Analysis & key factors

  • Atletico Madrid vs. Real Madrid odds favor Real Madrid as slight road favorites at +100.
  • Real Madrid sit second in La Liga with five wins from six matches, scoring 17 goals.
  • Atletico Madrid scored at least two goals in each of its home games this season.

The Madrid Derby comes up this weekend. Atletico hosts Real on Sunday afternoon at Metropolitano, and we expect nothing but fireworks.

Here are more soccer picks.

How to Watch

  • When: Sunday, September 20, 2026, 10:15 AM ET
  • Where: Riyadh Air Metropolitano Stadium, Madrid, Spain
  • How to Watch: ESPN+ / ESPN Deportes

La Liga Odds

Match ResultOdds
Atletico Madrid+260
Tie+260
Real Madrid+100

Game Preview

After two losses suffered on the road, one in La Liga and the other in the UCL, Atletico bounced back, beating Real Sociedad in San Sebastian, 0-3, and then smashing Osasuna at home 4-0.

They are very confident at home this year, netting 8 goals in three La Liga fixtures. Their most recent win over Osasuna saw four different players find the back of the net: David, Lee Kang-In, Le Normand and Baena.

Real isn’t playing as many would expect, particularly on the road, yet they are winning. So far, Los Blancos have had 5 wins in 6 appearances, but their defense isn’t looking well at all.

Mourinho’s crew allowed at least a goal in all but one game this year. Real’s matches are efficient, and 6 of the 7 they’ve played this season ended with over 2.5 hits.

Atletico Madrid vs. Real Madrid Head to Head

Both teams have scored in 9 of the last 10 meetings between Atletico Madrid and Real Madrid. Last year, Real triumphed in the Super Cup, while both teams split honors in La Liga. Atletico was better at home, 5-2, and Real won at Bernabeu 3-2.

Atletico Madrid vs. Real Madrid Predictions

We aren’t picking the winner here, but go with high efficiency. Both teams scoring and over 2.5 goals is the best bet. Both sides are in strong offensive rhythm, and the history suggests goals, so this pick is logical.

  • Free La Liga picks: Both teams to score & over 2.5 goals
Topics:

Soccer

More Predictions

Soccer Insight

MLS Predictions: Decision Day Best Bets, Odds & Picks for Saturday, Nov 7

Best pick: Inter Miami vs. Charlotte FC, Inter Miami (-270) Best BTTS: CF Montreal vs. Vancouver Whitecaps, Yes (-200) Best over/under: FC Cincinnati vs. Nashville SC, Under 3.5 Goals (-137) MLS parlay: Inter Miami, Philadelphia, Vancouver, Nashville (+802) Claim Up to $250 Free Bet at BetOnline It’s Decision Day in MLS. All 15 games kick […]

Alex Dudley 4 min read

Soccer Insight

Liga MX Predictions: Best Bets, Odds & Picks For Apertura Matchday 16

Best pick: Atletico de San Luis vs. FC Juarez, San Luis (-134) Best over/under: Tigres vs. Cruz Azul, Over 2.5 Goals (+103) Liga MX parlay: San Luis, Queretaro, Club America (+570) Claim Up to $250 Free Bet at BetOnline The Apertura is down to its final two weekends, and Matchday 16 is packed with games […]

Alex Dudley 4 min read

Soccer Insight

UEFA Champions League Matchday 4 Predictions: Best Bets, Total Goals & Handicap Picks

The 2026–27 UEFA Champions League league phase came to its midpoint as Matchday 4 (November 3–4, 2026) kicks off this Tuesday. 18 matches are ready for bettors, yet several attract more attention, and therefore a higher volume of wagers. Atletico Madrid hosts Bayern Munich at the Metropolitano, Barcelona welcomes Aston Villa at Camp Nou, while […]

Nikola Velickovic 5 min read

Soccer Insight

Liga MX Picks: Red Hot Cruz Azul After Another Win Over Club Leon

Up to $250 Free Bet, No Rollover Players accepted from all states (excluding NJ) Bet on the NFL Today Cruz Azul is third in the Liga MX standings and awaits Club Leon, who sit 6th. Their previous games have brought high efficiency and goals on both ends, therefore, we expect the same this Sunday night. […]

Nikola Velickovic 2 min read

Soccer Insight

MLS Picks Oct 31-Nov 1: Best Bets, Odds and Predictions for Every Match

Best pick: Columbus Crew to win vs D.C. United (-298) Best BTTS pick: Charlotte vs Orlando City, Yes (-357) Best over/under: LAFC vs Minnesota United, Over 3 goals (-121) MLS parlay: Columbus, LAFC, Orlando City and Inter Miami to win (+1655) Claim Up to $250 Free Bet at BetOnline The pressure is on in MLS […]

Alex Dudley 4 min read