Best MLS Bets & Parlay Picks For This Weekend (Aug 22-23)

A busy week of MLS action concludes this weekend, as all teams across the Eastern and Western Conferences will be in action. There will be a range of value plays after considering the MLS betting odds and you can find our MLS picks and parlay bets for this weekend’s action here.  

MLS Parlay Picks

• Inter Miami, LAFC, FC Cincinnati, NY Red Bulls, and Atlanta United All To Win (+1400)

MLS Best Bets For This Weekend

Inter Miami to Win vs. Toronto FC

Inter Miami will be one of the logical selections to include in MLS parlays this weekend. Despite a patchy run of form, which included a 4-1 loss against Nashville last Saturday, the Herons have been consistent in their matches at Nu Stadium.

Inter have avoided defeat in seven of their eight at their new stadium, and their attacking threat has continued to dazzle with 2.63 goals scored per game. Toronto’s season has been very underwhelming, with many of their major issues coming on the road after losing five of their nine MLS fixtures.

LAFC to Win vs. Portland Timbers

LAFC will be back at BMO Stadium this weekend, as they have a point to prove after dropping to third in the Western Conference standings. Their form since the World Cup has largely been positive, winning three of their five fixtures.

However, it is their record at home that makes them hard to oppose this weekend. LAFC have won seven of their eleven at BMO Stadium, showing defensive strength with just 0.91 goals conceded per match.

ALSO SEE: Premier League 2026/27: Our Experts Make Their Winner, Relegation, and Top Scorer Picks

FC Cincinnati to Win vs. Seattle Sounders

FC Cincinnati have been a prominent selection when making MLS parlay picks in recent weeks, and the strength of their form ensures that they are still a standout selection.

Cincinnati have avoided defeat in five of their previous six MLS fixtures, while the Seattle Sounders have been in miserable form since the World Cup with defeats suffered in each of their last seven in the MLS. It is also notable that the Sounders have fallen to losses in each of their previous four on the road.

NY Red Bulls to Win vs. Chicago Fire

A value play to consider this weekend is the NY Red Bulls to overcome the Chicago Fire. The defensive approach of the Bulls could hinder the Fire’s attacking quality, ensuring that the preference is for the hosts.

A return to form will be required after losing three of their previous four, but the Red Bulls have avoided defeat in three of their last four at home.

Atlanta United to Win vs. Sporting KC

Atlanta United could be the riskiest play to consider when making MLS parlay picks this weekend. United ended a poor run of form with a home win last weekend, and being back in front of their own fans could once again work in their favor on Sunday.

Atlanta have avoided defeat in four of their nine home fixtures in 2026, while Sporting KC have underperformed on their travels with just two wins in their ten fixtures, and allowing 3.1 goals per game.

MLS Parlay Picks

• Inter Miami, LAFC, FC Cincinnati, NY Red Bulls, and Atlanta United All To Win (+1400)