MLS: Orlando City vs. Columbus Crew Picks, Odds, and Preview (Oct 4)

The action in the Eastern Conference is reaching its conclusion in the regular season, with all nine playoff spots now filled. However, an important clash in the race to avoid dropping into a wild-card round is set for Oct 4, as Orlando City and Columbus Crew collide. You can find our picks for the clash here.

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Event Overview

• When: Saturday, October 4, 2025. 7:30 PM ET
• Where: Inter&Co Stadium, Orlando
• How to Watch: Apple TV

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Orlando City vs. Columbus Crew Odds

Match Result	Odds
Orlando City	-113
Draw	+310
Columbus Crew	+265

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Head-to-Head Record

Orlando holds the slender advantage based on previous encounters between the sides. That includes a 3-1 success on the road in the latest clash in July 2025. That success ended a three-game losing sequence against the Crew.

ALSO SEE: Alfred Dunhill Links Championship Picks, Odds, and Preview (Oct 2-5)

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Match Preview

Despite the nine playoff spots being filled in the Eastern Conference, there will remain pressure on teams as they look to avoid dropping into a wild-card round. The Columbus Crew currently sit ninth in the Eastern standings, but they are just two points adrift of their rivals this weekend.

The Crew have failed to win in their last three MLS matches, and they were easily swatted aside by Chicago last weekend. Despite having just under half of the possession, Columbus rarely threatened in an attacking sense after managing to record just a single shot on target.

Orlando City sit in the final automatic qualifying spot for the playoffs at present, but they have been held to draws in two of their last three matches. Still, confidence would have been gained from their 1-1 result against FC Cincinnati last time out.

Orlando’s attacking threat has been apparent throughout the 2025 season, failing to score in just 13% of their matches. Meanwhile, they have excelled in home matches in the MLS, scoring an average of 2.27 goals per game. However, defensively, they have been weak, also allowing a high average of 1.53 efforts per 90.

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Orlando City vs. Columbus Crew Picks

There will be increased pressure on both of these sides in the MLS this weekend, as both look to avoid dropping into the wild-card round. However, Orlando’s excellent home record could ensure that they have the quality to gain maximum points against the Crew.

Free Pick:

• Orlando City (-113)