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Expert prediction

NFL Week 4: Bengals vs. Broncos Preview, Odds, Picks (Sep 29)

  • Nikola Velickovic
  • Sep 24, 2025 at 5:05 AM EDT

Pick rationale

Analysis & key factors

  • Bengals vs. Broncos game closes NFL Week 4.
  • The Cincinnati Bengals are the worst running team in the league.
  • Denver Broncos lost back-to-back games.

The Broncos are pretty much always favorites at the Mile High, especially in this case when the rival’s starting QB is out.

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How to Watch

  • When: Monday, September 29, 8:15 pm ET
  • Where: Mile High, Denver, Colorado
  • How to Watch: ABC

Bengals vs. Broncos Odds

TeamMoneylineSpreadTotals
Bengals+290+7.544.5
Broncos-380-7.544.5

Game Preview

The Bengals were trashed in Minnesota against the Vikings, 48-10, in a game that showed why QB Jake Browning isn’t starter material. He had 140 passing yards for a TD, but was picked twice.

Cincinnati had 5 turnovers, as three more players fumbled for the guests besides Browning’s picks. When we add that the Bengals had just 53 rushing yards, such a high defeat wasn’t strange at all.

The Broncos lost to the Chargers in an exciting game, 23-20. Cameron Dicker’s 43-yard field goal as time expired sealed the second straight loss for Sean Payton’s boys. But overall, the Broncos played a good game, and it wouldn’t be unfair even if they won here.

RB JK Dobbins had 82 rushing yards for one touchdown, and he currently has 222 rushing yards in three events. WR Courtland Sutton posted 118 passing yards with one touchdown reception, while LB Nik Bonitto had two sacks.

Bengals vs. Broncos Head to Head

The Denver Broncos lead the series 22-12, but the Bengals won the last two games. Most recent during the previous season, 30-24 after OT at home.

Bengals vs. Broncos Predictions

Cinci is an underdog here, and will be in every match without Burrow. As for the Broncos, they are always very nasty at home, and we are certain they won’t miss this chance to post a win.

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