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MLS: Nashville vs. Houston Dynamo Picks, Odds, and Preview (Sep 27)

  • Alex Dudley
  • Sep 25, 2025 at 5:33 AM EDT

Pick rationale

Analysis & key factors

Cross-conference action is set for the MLS on September 27, and there will be huge ramifications in the playoff picture when Nashville and the Houston Dynamo collide. You can find the odds and picks for the matchup here.


How To Watch

  • When: Saturday, September 27, 2025, at 8:30 PM ET
  • Where: Geodis Park, Nashville
  • How To Watch: Apple TV

Nashville vs. Houston Dynamo Odds

Match ResultOdds
Nashville-147
The Draw+308
Houston Dynamo+376

Head-to-Head Record

A fifth meeting between Nashville and Houston is set for this weekend. The Dynamo recorded a win in the latest encounter between the teams, but that 2-1 success was recorded back in October 2022.


Match Preview

The pressure will continue to increase this weekend, as teams in the MLS look to secure their spot in the playoffs. Nashville remains in a prominent position in the Eastern Conference, as they sit seventh. However, they are now level on points with one of the two teams in the wild-card positions.

The home team this weekend have endured a dip in form in recent weeks, suffering defeats in each of their last three in the MLS. It could also be argued that they may have their attentions set to next week’s U.S. Open Cup final against Austin.

READ More: USA Today 301 Picks, Odds, and Preview (Sep 21)

This weekend could also be crucial for the Houston Dynamo, as they remain in the fight for a playoff spot in the Western Conference. They come into this round sitting tenth, and a victory on Saturday could see them end the weekend as high as eighth in the rankings.

The Dynamo have found victories harder to come by in recent weeks, winning just one of their last three, and two of their previous seven since the conclusion of the Leagues Cup. But, they were 1-0 victors in their latest outing against the Portland Timbers.


Nashville vs. Houston Dynamo Picks

There could be an angle in taking on the home team this weekend, as they have an important domestic cup final to prepare for next week. Houston have been hard to beat in recent weeks, and the confidence of last weekend’s victory could get them over the line in Tennessee.

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