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Expert prediction

NFL Week 5: Broncos vs. Eagle Preview, Odds, Picks (Oct 5)

  • Nikola Velickovic
  • Sep 30, 2025 at 7:21 PM EDT

Pick rationale

Analysis & key factors

  • Broncos vs. Eagles total is 43.5 points
  • The Philadelphia Eagles are undefeated at 4-0.
  • Broncos’ QB Bo Nix is under pressure to step up.

There’s no championship hangover among the Eagles, who are perfect at the moment. They now host the inconsistent Denver Broncos this Sunday.

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How to Watch

  • When: Sunday, October 5, 1 pm ET
  • Where: Lincoln Financial Field, Philadelphia, Pennsylvania
  • How to Watch: CBS

Broncos vs. Eagles Odds

TeamMoneylineSpreadTotals
Broncos+160+3.543.5
Eagles-190-3.543.5

Game Preview

Bo Nix is taking fire, and despite a good job against the weakened Bengals and a 28-3 win, the fans aren’t too pleased with him this year. He had two touchdown passes and one rushing TD, with one pick. In total, Nix generated 326 passing yards last weekend.

Yet overall, the fans think he’s not stepping up in important moments. So far, he has had 7 touchdown passes and four picks this year. And the Bengals lost some games due to his decisions.

As for the Eagles, the word “loss” is something unknown this year. They had solid rivals, like Dallas, Kansas City, LA Rams, and the Buccaneers, and beat them all. The Chiefs and the Bucs on the road.

Jalen Hurts is one of the top MVP favorites, having 5 TD passes so far without a single pick, and rushing for four more. He has 609 passing and 179 rushing yards at the moment.

Broncos vs. Eagles Head to Head

This rivalry has spanned 14 games, and the current record stands in favor of the Eagles, 9-5.

Broncos vs. Eagles Predictions

With Nix performing as he does in big games, and the Eagles’ current form, this game has only one outcome in our opinion: Philadelphia’s victory. Right now, Hurts and the boys are at least one level above Denver, and we advise betting on them covering a 3.5-point spread.

  • Free NFL picks: Eagles -3.5
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