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Expert prediction

NFL Week 6: Eagles vs. Giants Preview, Odds, Picks (Oct 9)

  • Nikola Velickovic
  • Oct 6, 2025 at 1:05 AM EDT

Pick rationale

Analysis & key factors

  • Eagles vs. Giants TNF odds favor the guests at -380.
  • The Philadelphia Eagles lost to the Chargers last Sunday, 21-17.
  • Giants’ QB Jaxson Dart had three turnovers against the Saints.

Thursday Night Football brings us the battle between two NFC East teams, in which the Giants host the Eagles.

If you want more NFL odds and predictions, please follow this link.

How to Watch

  • When: Thursday, October 9, 8:15 pm ET
  • Where: MetLife Stadium, East Rutherford, New Jersey
  • How to Watch: Prime Video

Eagles vs. Giants Odds

TeamMoneylineSpreadTotals
Eagles-380-7.541.5
Giants+290+7.541.5

Game Preview

The fact that the Eagles (4-1) lost for the first time this year is enough to set the alarm off in Philly. Jalen Hurts and the boys had a 14-point lead against the Broncos, yet lost in the end, 21-17. Denver completely stopped the Eagles’ running game, allowing only 45 yards on the ground.

Unlike any other game this year, Hurts was very dominant in the air, throwing for 280 passing yards and 2 touchdowns, yet he ran for only 3 yards. Just to mention that the Eagles are the 2nd-worst team in the league in passing yards won, 161.8 per game.

Without injured Malik Nabers, the Giants (1-4) will have an extremely tough future. QB Jaxson Dart learned that in New Orleans, where the Saints beat the NYG, 26-14. Dart had 202 passing yards, for 2 touchdowns and interceptions.

Though, he ran for 55 yards, while RB Cam Skattebo generated 59 yards, and the Giants ended the night producing 136 rushing yards. Tight end Theo Johnson would have only 33 receiving yards, though, with 2 touchdowns.

Eagles vs. Giants Head to Head

Philly leads the all-time series, 95-88-2, with the Eagles winning both games last year, 28-3 in New York and 20-13 at home.

Eagles vs. Giants Predictions

Philadelphia is a favorite here, and even though they struggle to find the rhythm on the offensive side, their individual quality should be enough to dispatch the Giants easily. We take the Eagles to cover the spread here.

Free NFL Picks: Eagles -7.5

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