Skip to content

Expert prediction

NFL Week 10: New Orleans Saints vs. Carolina Panthers Preview, Odds, Picks (Nov 9)

  • Nikola Velickovic
  • Nov 5, 2025 at 3:58 AM EST

Pick rationale

Analysis & key factors

  • Saints vs. Panthers game odds favor Carolina at -240.
  • QB Tyler Shough starts for the New Orleans Saints.
  • Bryce Young is 5-0 since the start of October.

The Panthers are in an excellent position here, as they host the weakest team in the NFC South. With a triumph over the divisional rivals, Carolina could severely improve its playoff prospects.

If you want more NFL odds and predictions, please follow this link.

How to Watch

  • When: Sunday, October 9, 1 pm ET
  • Where: Bank of America Stadium, Charlotte, North Carolina
  • How to Watch: FOX

Saints vs. Panthers Odds

TeamMoneylineSpreadTotals
Saints+200+5.539.5
Panthers-240-5.539.5

Game Preview

The Saints are apparently after the top pick in the following NFL Draft. With a 1-8 record, this team is dead last in the NFC, and that’s why they decided to switch quarterbacks and allow Tyler Shough to show his worth.

His debut wasn’t that great, because the Rams rolled over New Orleans in LA, 34-10. Shough had 176 passing yards for one TD and one intercepted pass. We have to say that OT Trevor Penning and WR Rashid Shaheed were both traded this Tuesday night.

The Panthers are positive, and what’s more important, Bryce Young has won five games in a row right now. He was out, and Andy Dalton played in a 40-9 defeat to the Bills, meaning that the former No. 1 pick is unbeaten since the start of October.

The previous weekend, the Panthers’ defense did the job in Green Bay, holding the hosts to 13 points, while the offense delivered 16. Young had 102 passing yards for one interception, but Rico Dowdle ran for 130 yards and two touchdowns. He’s been incredible this year.

Saints vs. Panthers Head to Head

After 61 games, the Saints lead the series, 32-29. Last year, the Saints won at home, 47-10, while the Panthers triumphed in Charlotte, 23-22.

Saints vs. Panthers Predictions

New Orleans traded some of their players, and we believe the Saints are slowly preparing for the next season. This is excellent news for the Panthers, who must win here and who, overall, are a better team. So it’s Carolina to cover a 5.5-point spread.

Topics:

NFL

More Predictions

NFL Insight

NFL Week 9 Upsets: Commanders Nasty Underdogs, Cardinals and Raiders Defending the Spread

Week 9 of the 2026 NFL season features several situational spots where short underdogs hold tactical, scheduling, or matchup advantages. There aren’t as many choices as in previous rounds, but there’s still enough for us bettors to make some money. Here is one straight-up upset pick and two point-spread underdog picks, backed by key tactical […]

Nikola Velickovic 3 min read

NFL Insight

NFL Week 9 Player Props: Pitts to Score a TD, Flournoy Continues to Grow

NFL Week 9 player props are here. We’ve waited to see the situation regarding potential absences and injuries, and with game day just around the corner, it was time to unleash the best player prop picks for this round. We have three selections for our bettors, carefully picked and evaluated following a thorough process. After […]

Nikola Velickovic 2 min read

NFL Insight

Broncos vs. Panthers Week 9 Picks: Young’s Poor Protection Will Cost Carolina

Best bet: Broncos ATS pick: Broncos -2.5 Bet Broncos vs. Panthers at BetUS Denver Broncos (6-2) hit the road to face the Carolina Panthers (3-4) and continue their excellent run. The Panthers have been on the downhill lately and are under pressure to win this game and get back to the winning side. Stay with […]

Nikola Velickovic 2 min read

NFL Insight

Giants vs. Eagles Week 9 Picks: Rested Giants After a Win in Philly

Best bet: Giants ATS pick: Giants -3.5 Bet Giants vs. Eagles at BetUS NFC East is completely wild these days. The New York Giants (4-2-1) lead the group, while the Philadelphia Eagles (2-6) sit last. The home team is in huge trouble, having multiple stars out due to injuries. The Giants also have some absences, […]

Nikola Velickovic 2 min read

NFL Insight

Browns vs. Saints Week 9 Picks: Indoor Arena Will Create Problems for Cleveland

Best bet: Saints -1.5 Straight up pick: Saints moneyline Bet Cardinals vs Cowboys at BetUS Cleveland Browns (5-3) are still in the mix for the playoffs. However, they will need to win in New Orleans against the Saints (2-5). Browns are very light underdogs here, sitting at +100 before we started writing this article. We […]

Nikola Velickovic 2 min read