Expert prediction
NFL Week 11: San Francisco 49ers vs. Arizona Cardinals Preview, Odds, Picks (Nov 16)
Pick rationale
Analysis & key factors
- 49ers vs. Cardinals odds favor the Niners, -145.
- San Francisco is the No.1 passing team in the NFL, with 261.4 passing yards per game.
- Jacoby Brissett is the Cards’ starting QB.
Two NFC West teams are in serious trouble. The Niners, due to all the injuries they have suffered this year, and the Cardinals, because of inconsistency and various other on- and off-field issues.
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How to Watch
- When: Sunday, November 16, 4:05 pm ET
- Where: State Farm Stadium, Glendale, Arizona
- How to Watch: FOX
49ers vs. Cardinals Odds
Game Preview
If there’s a team in the NFL cursed with injuries, that’s San Francisco. But the Niners are still battling and are in the playoff picture. This game will be extremely important for them to stay there. With a win they’ll not only push down the Cards, but keep themselves in the race to reach the top of the division.
Christian McCaffrey is the only top star left on the team, and he’s doing everything in his power to lead his team. CMC has 626 rushing yards and 692 receiving yards.
Cardinals are facing some big changes. Kyler Murray is no longer the No.1 QB and is likely to exit Arizona at the end of the year. Jacoby Brisset is a starter now, but check this out. In the last three games he played, the opponents sacked him 16 times. So, to be honest, the Cards’ O-Line is terrible.
This is Arizona’s last chance to get back in the playoff race. If they lose here, that will be the end of this year’s hopes.
49ers vs. Cardinals Head to Head
Another NFC West division rivalry. The 49ers have 37 wins, while the Cardinals have 31. They already met this season, and the 49ers won at home, 16-15.
49ers vs. Cardinals Predictions
The Niners have a better offense. As far as the defenses are concerned, they are somewhat the same, but what might be the difference here is that the Cards’ O-Line cracks more frequently than the Niners.
- Free NFL Picks: 49ers Win
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