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Expert prediction

NFL Week 11: Detroit Lions vs. Philadelphia Eagles Preview, Odds, Picks (Nov 16)

  • Nikola Velickovic
  • Nov 12, 2025 at 4:41 AM EST

Pick rationale

Analysis & key factors

  • Lions vs. Eagles odds favor Philadelphia at -140.
  • Detroit Lions score the second-most points per game, 31.4.
  • The Philadelphia Eagles have won 3 games in a row.

Week 11 Sunday Night Football is in Philly, where the champions host the Detroit Lions.

If you want more NFL odds and predictions, please follow this link.

How to Watch

  • When: Sunday, November 16, 8:20 pm ET
  • Where: Lincoln Financial Field, Philadelphia, Pennsylvania
  • How to Watch: NBC, Peacock

Lions vs. Eagles Odds

TeamMoneylineSpreadTotals
Ravens+120+2.546.5
Browns-140-2.546.5

Game Preview

The Detroit Lions have been rather inconsistent lately, winning and losing consecutively in their past five matches. Though the good thing is that after losing to the Vikings at home, 27-24, they quickly bounced back to beat the Commanders on the road, 44-22.

The second offense in the NFL worked well, with Jared Goff posting 320 passing yards with three touchdown passes, and Jahmyr Gibbs rushing for 142 yards and two scores on the ground. The Lions had 226 running yards.

Eagles beat the Packers on the road, 10-7, posting a huge win and maybe making the turning point of the year. They had a grueling first half, which saw no points, and eventually DeVonta Smith cracked the Packs. He had 69 receiving yards and the sole TD of the game for the Eagles.

Philly’s defense was up to the task, having three sacks and forcing two turnovers, both from fumbles. Jordan Love was harassed all the time and was without a proper rhythm.

Lions vs. Eagles Head to Head

There were 36 games between these teams, and the Eagles won 18, two more than the Lions. Also, there were two ties.

Lions vs. Eagles Predictions

Detroit Lions have been on fire when it comes to scoring, but we are pretty sure that the Eagles have enough weapons to respond here. The Over/Under line is set at 46.5 points, and we believe this one is going over.

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