Expert prediction
AFC Wild Card: Buffalo Bills vs. Jacksonville Jaguars Preview, Odds, Picks (Jan 11)
- Nikola Velickovic
- Jan 5, 2026 at 4:00 AM EST
Pick rationale
Analysis & key factors
- Bills vs. Jaguars odds favor Buffalo by 1.5 points.
- The total is 51.5 points.
- Jags have 8 wins in a row.
A high-octane matchup awaits us in Jacksonville, where the Jags host the Bills in the AFC Wild Card round.
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How to Watch
- When: Sunday, January 11, 1 pm ET
- Where: EverBank Stadium, Jacksonville, Florida
- How to Watch: CBS
Bills vs. Jaguars Odds
Game Preview
The Buffalo Bills are on the rise, winning 5 of the last 6 games, and looking pretty fired up. They are all about James Cook III, who ended up as the No.1 rusher with 1,606 yards this year. He has 12 touchdowns on the ground as well.
Apart from the loss to the Eagles, 13-12 at home, the Bills’ offense was excellent, posting 35+ points in three of the past 5 games. After a shaky start, Buffalo looks much better now.
Bills at Jaguars at 1pm Sunday. Here's the schedule: pic.twitter.com/ynq36wy4E4
— Sal Capaccio 🏈 (@SalSports) January 5, 2026
As for the Jags, they are also very efficient on offense, scoring under 27 points just twice during their 8-game winning streak. The versatility of the Jags’ attack needs to be mentioned, as they combine all the resources available perfectly.
Trevor Lawrence definitely played the best season of his career, having 3,752 passing yards for 26 TDs and 12 picks, but he ran for 348 yards and 9 touchdowns.
Bills vs. Jaguars Head to Head
After 20 games overall, the series is tied at 10 all. The last meeting was in 2024, when Buffalo blew the Jags away 47-10 at home.
Bills vs. Jaguars Predictions
Buffalo Bills come to Jacksonville in excellent offensive mood, but the hosts are looking perfect too. Even though it’s playoffs, we are all in on OVER 51.5 points here, because these two teams are relying upon offense these days.
- Free NFL Picks: Over 51.5 points
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