Expert prediction
NFL Odds, Predictions: Chargers vs. Seahawks Week 4 Preview & Picks (Oct 4)
Pick rationale
Analysis & key factors
- Chargers vs. Seahawks Week 4 odds clearly favor Seattle at -355.
- LAC has the 4th-worst scoring offense in the NFL, 14.7 ppg.
- Seattle allows the fewest total yards per game, 228.7.
The Chargers are in deep trouble, as they can’t find rhythm or consistency. On top of that, LAC heads to Seattle to meet the Super Bowl champions, the Seahawks.
You can view the full slate of NFL Week 4 odds.
How to Watch
- When: Sunday, October 4, 2026, 4:25 PM ET
- Where: Lumen Field, Seattle, Washington
- How to Watch: CBS
Chargers vs. Seahawks Odds
Game Preview
Chargers are one of the worst offenses in the league, scoring only 14.7 points per game. This ranks them 29th in the NFL. Head coach Jim Harbaugh’s offense is terrible in fourth-quarter scoring efficiency, delivering only 3 points in the first three quarters.
Justin Herbert threw for 627 yards, 3 TDs, and 4 interceptions. Meanwhile, the Chargers have no run game, with their top rusher, Omari Hampton, totaling just 193 yards across three games.
Sam Darnold is back for the Seahawks, who lost to the Commanders 33-31 in Washington. The Super Bowl champions suffered a defeat because of 3 turnovers, 2 of them Darnold’s interceptions. He finished with 379 passing yards and 4 TDs, along with those two picks.
The run game was awful, providing just 44 yards. First-round rookie RB Jadarian Price had 15 on 5 carries; Emanuel Wilson had 14 in 9 rushes.
Chargers vs. Seahawks Predictions
With Darnold back behind the wheel and with the home-field edge, the Seahawks should easily defeat the struggling rivals. LAC is currently experiencing multiple problems therefore, the champs will win and cover the spread.
- Free NFL pick: Seattle Seahawks -6.5
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