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NFL Odds, Predictions: Texans vs. Titans Week 5 Preview & Picks (Oct 11)

  • Nikola Velickovic
  • Oct 5, 2026 at 4:14 AM EDT

Pick rationale

Analysis & key factors

  • Texans vs. Titans odds favor Houston at -300.
  • Both teams are 0-4.
  • Texans are the biggest disappointments of the season so far.

Two teams in the AFC South are winless after 4 rounds, and they meet in Nashville this Sunday. Texans head to face the Titans at Nissan Stadium, with both teams aiming to improve an awful impression after one month of NFL football.

Here is the full NFL Week 5 odds and picks list.

How to Watch

  • When: Sunday, October 11, 2026, 1:00 PM ET
  • Where: Nissan Stadium, Nashville, Tennessee
  • How to Watch: CBS

Texans vs. Titans Odds

TeamMoneylineSpreadTotals
Texans-300-6.539.5
Titans+240+6.539.5

Game Preview

Texans’ loss to the Cowboys at home last week, 34-30, wasn’t because of CJ Stroud, but because of poor defense. What was the best defensive unit in the league last season can’t defend the pass and is 28th in the NFL, allowing 260 passing yards per game.

The loss vs. Dallas also came from a very bad run game, which produced just 62 yards. RB David Montgomery had only 24 yards on 10 carries, which is terrible for a No.1 rusher.

Titans fought bravely in Baltimore, losing to the Ravens, 24-18. The difference this time was that Tennessee had 2 turnovers, while their rivals committed none. Though, we have to say that the two-time NFL MVP Lamar Jackson, went out early due to an injury.

Cam Ward has to do better. The former No.1 pick threw for 222 yards, one pick, and one touchdown. He has 726 yards in 4 games, with 3 TD passes and two picks. No matter the circumstances, these numbers show that Ward’s progress isn’t as planned. That puts additional pressure on him.

Texans vs. Titans Predictions

This game will be a perfect opportunity for the Texans to regain defensive confidence and for Stroud to build momentum. We respect Saleh and the Titans, but Ward isn’t competitive enough right now, even against a shaken Texans team.

How to bet on the Texans vs. Titans (Week 5)

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