Expert prediction
MLB: Mariners vs Guardians Odds, and Picks (Apr 7)
Pick rationale
Analysis & key factors
- The Mariners fell short against the Angles, losing by a score of 4-3.
- Cleveland improved to 5-2 on the season with a win over Oakland.
- The Guardians are 243-199 in their all-time history against the Mariners.
Seattle (2-5) and Cleveland (5-2) face off in a solid AL matchup. The Guardians are off to a hot start, and will aim to continue it against Seattle. Meanwhile, the Mariners are trying to repeat last season’s success.
Jump to:
How to Watch
- Where: Progressive Field, Cleveland, OH
- When: Friday, April 7, 2023, at 2:20 p.m ET
- How to Watch: Bally Sports
Odds
| Team | Moneyline |
| Mariners | |
| Guardians |
Game Preview
Seattle came up short against the Angles, dropping their second straight series to start the year. The Mariners have now gone 1-5 since their Opening Day shutout against the Guardians, and will have to head on the road for their next 6 games. They’re looking to improve on an exceptional season last year, where they won 90 games and made the playoffs for the first time since 2001. They need to get back on track.
The Guardians picked up their 5th win in their last 6 games, defeating the Athletics and winning their second straight series. They’re on a complete opposite trajectory as the Mariners following their Opening Day bout, and will have an opportunity to further the gap between them with a home series here. Cleveland’s hot start has ignited hopes that they could finally be returning to a World Series capable team.
Prediction
These two teams have been headed in opposite directions ever since Opening Day. They’ve already played a series against each other this season, with the Guardians winning 2-1 in Seattle. Now back in Cleveland, they should have even more success. I’m not certain that a sweep will happen, but I feel pretty good about picking the Guardians to win both this game and the series as a whole against the Mariners.
MLB Picks:
MLB
More Predictions
World Series: Rays vs. Brewers Game 4 Picks, Odds & Betting Analysis
There is a sense of inevitability in the 2026 World Series, as Milwaukee Brewers require just one more victory to win the biggest MLB honor for the first time. History will be against the Tampa Bay Rays, as no team has ever recovered from 3-0 down to win the World Series. You can find the […]
World Series: Rays vs. Brewers Game 3 Picks, Odds & Betting Analysis
The intense action in the World Series steps up a gear on Monday, as the first game of the series to see the Tampa Bay Rays have home-field advantage will be staged. It will be a must-win encounter for the hosts, following defeats in Games 1 and 2 at American Family Field. A victory for […]
World Series: Brewers vs. Rays Game 2 Picks, Odds & Betting Analysis
The intensity increases in the World Series on Saturday evening, as Game 2 between the Milwaukee Brewers and Tampa Bay Rays is set for American Family Field. Milwaukee will be hoping for a fast start in their opening two games, but the Rays have been consistent on their travels in the postseason. The latest odds […]
World Series: Brewers vs. Rays Game 1 Picks, Odds & Betting Analysis
The high-pressure action in the MLB reaches new heights on Oct. 23, as the 2026 World Series gets underway. Both the Tampa Bay Rays and Milwaukee Brewers will be targeting first honors, and whichever team deals with the pressure the best will likely seize the advantage. The Brewers will have the Game 1 home-field advantage, and you […]
World Series 2026: Brewers vs. Rays Picks, Series Odds & Betting Analysis
History awaits in the MLB postseason, as a first-time World Series champion will be crowned in 2026. The Tampa Bay Rays are hoping that it’s their third time lucky, having lost in the 2008 and 2020 World Series, while the Milwaukee Brewers chase a first honor in their return to the World Series for the […]