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Expert prediction

No. 6 Iowa State vs No. 2 Arizona Preview, Odds, Predictions (March 2)

  • Richard Pereira
  • Mar 2, 2026 at 4:25 PM EST

Pick rationale

Analysis & key factors

  • The Cyclones remain inside the top 10 of the latest AP poll.
  • The Wildcats are rolling with four consecutive wins in league play.
  • This marks the 10th all-time matchup between the two Big 12 squads.

The Big 12 will be quite active in the night hours of the March 2 slate when the No. 2 Arizona Wildcats host the No. 6 Iowa State Cyclones. The hosts come out as the solid favorite, paving the way for a great showdown between two of the 10 best performing teams in the country.

How to Watch

  • When: Monday, March 2, 9 pm ET
  • Where: McHale Center, Tucson, Arizona
  • How to Watch: ESPN

NCAA Matchup Odds & Lines

TeamOddsSpreadTotals
Iowa State-105+7O149.5
Arizona-115-7U149.5

Game Preview

The No. 4 Cyclones (24-5, 11-5 Big 12) suffered a minor setback, losing in a ranked upset to the Texas Tech Red Raiders. Despite the defeat, Iowa State remains firm within the top 10 of the AP Top 25. Joshua Jefferson has recorded two triple-doubles this season, tied for the most in the country, presenting himself as a key threat for a potentially big performance. Meanwhile, Milan Momcilovic has been the nation’s best marksman this season, as the junior leads the country in 3-point percentage. He has six 25-plus point games so far this season for the Cyclones.

The No. 2 Wildcats (27-2, 14-2 Big 12) are back in control as an elite squad, racking up ranked wins over BYU, Houston and Kansas. Brayden Burries is on the Naismith Trophy Late-Season Watch List; he has scored 20+ points 10 times this season and averaged 16.9 points on 47% FG shooting and 39% 3FG shooting for the month of February. Meanwhile, Anthony Dell’Orso shot 22.8% from the 3-point line in December and January (13 of 57); In February, he shot 40% from long range (12 of 30) and 50% overall from the floor.

Iowa State vs Arizona Head-to-Head

The two programs have had nine meetings in their history, and the result is 5-4 for the Wildcats. The last matchup was in March 2025 when Iowa State won 84-67 at home.

Iowa State vs Arizona Predictions

Arizona already has a share of the Big 12 regular-season title secured but has desires to win the title outright. A win here would grant them the opportunity, especially as they honor their senior players in the home finale. It will be tough for Iowa State to pull off a road upset in such hostile territory, but they will surely try to have the game go down to the wire. Our betting pick here is the Wildcats to cover a 7-point spread.

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