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Expert prediction

NFL Odds, Predictions: Eagles vs. Bears Week 3 Preview & Picks (Sep 28)

  • Nikola Velickovic
  • Sep 25, 2026 at 2:52 AM EDT

Pick rationale

Analysis & key factors

  • Eagles vs. Bears MNF odds favor Philly at -225.
  • Chicago has put up 425 rushing yards in the first two games.
  • Eagles are 2-0.

Monday Night Football will tell us a lot of things. Are the Eagles title contenders? How strong is Chicago? Can these two sides win their respective divisions? All this and much more.

Check for more NFL odds and picks here.

How to Watch

  • When: Monday, September 28, 2026, 8:15 PM ET
  • Where: Soldier Field, Chicago, Illinois
  • How to Watch: ESPN / ABC / ESPN+

Eagles vs. Bears Odds

TeamMoneylineSpreadTotals
Eagles-225-4.541.5
Bears+185+4.541.5

Game Preview

The Eagles are consistent in scoring, delivering 24 points in both wins: vs. the Commanders, 24-22, and vs. the Titans in Nashville, 24-20. Both triumphs were narrow, but the team from Philly did well under pressure and showed its mental power.

Victory in Tennessee came with 9 seconds to go, when QB Jalen Hurts connected with Darius Cooper for a 3-yard TD. Hurts threw for 264 passing yards, 2 touchdowns, and 2 interceptions. Philly’s run game was poor, totaling only 89 yards in the game.

After scoring 59 points in the first meeting of the year against the Panthers, the Bears managed only 3 in the second. The Minnesota Vikings smashed Chicago, 20-3, at Soldier Field, raising questions about the unit’s current shape.

What’s worse for the Bears than the fans’ doubt is the fact that the starting QB Caleb Williams might miss this one. Even if he plays, some sources say he won’t be 100% fit because of his hamstring injury.

Eagles vs. Bears Predictions

Chicago has a lethal run game, but against the Eagles, that won’t work as well as against the Panthers or the Vikings. Also, the situation with Williams complicates Chicago’s game plan, and that is a huge reason to bet on the Eagles’ triumph here.

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