Expert prediction
NFL Odds, Predictions: Jaguars vs. Broncos Week 2 Preview & Picks (Sep 20)
Pick rationale
Analysis & key factors
- Jaguars vs. Broncos odds favor Denver by 2.5 points.
- Broncos allowed 220 rushing yards against the Chiefs.
- Trevor Lawrence threw for 4 TD passes.
This is yet another high-stakes matchup early into the season. The Jags and the Broncos won their respective AFC divisions last year, and the result of this matchup could have massive implications for the playoff picture.
Check for more NFL odds and picks here.
How to Watch
- When: Sunday, September 20, 2026, 4:05 PM ET
- Where: Empower Field at Mile High, Denver, Colorado
- How to Watch: CBS
Jaguars vs. Broncos Odds
Game Preview
Quarterback Trevor Lawrence had his day against the sorry Browns. Jags’ leader recorded 245 passing yards, 18/23, connecting his receivers with the end zone 4 times. On all 4 occasions, it was a different player.
The Broncos have a weak O-line, but still, we need to mention the 5 sacks the Jags posted. Trevon Walker and Josh Hines-Allen both had 1.5, with the latter adding 2 QB hits.
Broncos were blown into pieces on Monday Night Football against the Chiefs. Mahomes threw for 310 yards and 3 TDs, and Kansas City rolled over Denver in every aspect of play. Sean Payton’s boys allowed 220 rushing yards, something we haven’t seen for a long time.
Meanwhile, the Broncos had only 61 yards on the ground, while Bo Nix threw for 131 yards, for one TD and one pick. He would fumble the ball three times, once losing possession.
Jaguars vs. Broncos Predictions
Lawrence and the boys know how to win here, because they did that last year. Now, we didn’t like how the Broncos’ offense looked against the Chiefs, and even though Denver has a home-field edge, we will pick Jacksonville to defend the spread.
- Free NFL picks: Jaguars +2.5
NFL
More Predictions
NFL Week 9 Upsets: Commanders Nasty Underdogs, Cardinals and Raiders Defending the Spread
Week 9 of the 2026 NFL season features several situational spots where short underdogs hold tactical, scheduling, or matchup advantages. There aren’t as many choices as in previous rounds, but there’s still enough for us bettors to make some money. Here is one straight-up upset pick and two point-spread underdog picks, backed by key tactical […]
NFL Week 9 Player Props: Pitts to Score a TD, Flournoy Continues to Grow
NFL Week 9 player props are here. We’ve waited to see the situation regarding potential absences and injuries, and with game day just around the corner, it was time to unleash the best player prop picks for this round. We have three selections for our bettors, carefully picked and evaluated following a thorough process. After […]
Broncos vs. Panthers Week 9 Picks: Young’s Poor Protection Will Cost Carolina
Best bet: Broncos ATS pick: Broncos -2.5 Bet Broncos vs. Panthers at BetUS Denver Broncos (6-2) hit the road to face the Carolina Panthers (3-4) and continue their excellent run. The Panthers have been on the downhill lately and are under pressure to win this game and get back to the winning side. Stay with […]
Giants vs. Eagles Week 9 Picks: Rested Giants After a Win in Philly
Best bet: Giants ATS pick: Giants -3.5 Bet Giants vs. Eagles at BetUS NFC East is completely wild these days. The New York Giants (4-2-1) lead the group, while the Philadelphia Eagles (2-6) sit last. The home team is in huge trouble, having multiple stars out due to injuries. The Giants also have some absences, […]
Browns vs. Saints Week 9 Picks: Indoor Arena Will Create Problems for Cleveland
Best bet: Saints -1.5 Straight up pick: Saints moneyline Bet Cardinals vs Cowboys at BetUS Cleveland Browns (5-3) are still in the mix for the playoffs. However, they will need to win in New Orleans against the Saints (2-5). Browns are very light underdogs here, sitting at +100 before we started writing this article. We […]