Expert prediction
NFL Odds, Predictions: Broncos vs. Cardinals Week 7 Preview & Picks (Oct 25)
Pick rationale
Analysis & key factors
- Broncos vs. Cardinals odds favor Denver at -230.
- Arizona made a huge upset, beating the Rams in LA, 18-16
- The Broncos offense generates only 252.2 ypg, the second-worst in the NFL.
Cards beat the Rams on the road, which gave them a massive morale boost ahead of this event. Meanwhile, the Broncos are in excellent shape, with 4 wins in 5 weeks. Both teams aim for a triumph in Glendale, yet who will come out on top?
How to Watch
- When: Sunday, October 25, 2026, 4:05 PM ET
- Where: State Farm Stadium, Glendale, Arizona
- How to Watch: CBS, Paramount+
Broncos vs. Cardinals Odds
Game Preview
The Broncos struggle on offense, scoring only 19 points per game. However, their defense is there to step up when needed to stiff rivals, even though it doesn’t generate flashy numbers. Last weekend, they beat the champions, the Seahawks, 17-14 on TNF after OT.
We should note that Denver had a very respectable schedule, meeting the Jags, Rams, 49ers, Chargers, and Seahawks. And Sean Payton’s crew is well above .500, holding a 4-2 record.
The Cardinals stopped their 4-game losing streak by beating one of the Super Bowl favorites, the LA Rams. Arizona won 18-16 on the road, without scoring a single touchdown. Kicker Chad Ryland made all of his 6 field goals, the last with the time expiring to seal the win.
Arizona’s defense is the 3rd-worst in the league, allowing 29.7 points per game. Meanwhile, Jacoby Brissett is unstable and oscillates a lot. The Cardinals’ QB didn’t throw a single TD pass last week.
Broncos vs. Cardinals Predictions
Even though the Cardinals have momentum, we’re picking the Broncos here. They’ve faced much tougher rivals than Arizona and shown their quality. Denver’s defense will be enough for Brissett and the boys, even if Bo Nix and the offense aren’t at their best.
Free NFL pick: Broncos -2.5
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