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NFL Odds, Predictions: Rams vs. Eagles Week 4 Preview, Odds, Picks (Oct 4)

  • Nikola Velickovic
  • Sep 29, 2026 at 3:52 AM EDT

Pick rationale

Analysis & key factors

  • Rams vs. Eagles odds see the LA team as -150 favorites.
  • The Eagles are coming home after two straight road games.
  • Rams generate the most total yards per game in the NFL, 417.

The absolute game of the week is scheduled for Sunday in Philly, where the Rams visit the Eagles. Both teams are coming off losses and are under the imperative to win this contest.

You can view all the NFL Week 4 odds.

How to Watch

  • When: Sunday, October 4, 2026, 1:00 PM ET
  • Where: Lincoln Financial Field, Philadelphia, Pennsylvania
  • How to Watch: FOX

Rams vs. Eagles Odds

TeamMoneylineSpreadTotals
Rams-150-2.544.5
Eagles+125+2.544.5

Game Preview

Matt Stafford bombs downfield as he usually does; however, the former NFL MVP has 6 touchdowns and 4 interceptions in three games. Not what we got used to seeing when talking about him.

The Rams average 284 passing yards per game, the 2nd most in the NFL, and run for 133.7 yards, 7th overall. But the team struggles to stop the rivals in the end zone, and that’s the reason for 2 losses in three weeks.

Philadelphia is no longer flamboyant in any aspect of its game. They rank 23rd in scoring at 18.2 ppg and 16th in points allowed at 23 ppg. Their defense, which was one of the toughest over the past two years, is mediocre, but more importantly, the attack has deflated.

For instance, their run game has dropped sharply, and through the first three weeks, Hurts and Saquon Barkley combined for 261 rushing yards. They used to do that in one single game.

Rams vs. Eagles Predictions

This is a 50-50 game that can go either way when it comes to picking the winner. Though, we believe that the Eagles are going to bounce back at home, at least offensively, and that, on the other hand, we have one of the best and most diverse offenses in the NFL, so the final pick in this case is over 44.5 points.

  • Free NFL pick: Over 44.5 points

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