Expert prediction
NFL Week 10: Atlanta Falcons vs. Indianapolis Colts Preview, Odds, Picks (Nov 9)
- Nikola Velickovic
- Nov 3, 2025 at 1:53 AM EST
Pick rationale
Analysis & key factors
- Falcons vs. Colts NFL Week 10 game takes place in Berlin.
- Daniel Jones leads the way in the NFL with 2,404 passing yards.
- Falcons are the best pass defense in the NFL with 158.1 yards per game.
Colts lost to the Steelers last weekend, and they need a win over the Falcons to get back in the saddle and continue the race for the top seed in the AFC.
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How to Watch
- When: Sunday, November 9, 9:30 AM ET
- Where: Olympic Stadium, Berlin, Germany
- How to Watch: NFL NEt
Falcons vs. Colts Odds
Game Preview
The Falcons have suffered three losses in a row, with the most recent one coming in Foxborough, where the Patriots defeated them 24-23. Atlanta missed an extra point earlier, and that particular moment proved to be a key factor in the event, as it ultimately cost the Falcons dearly.
QB Michael Penix Jr. had a very good game, with 221 passing yards for 3 touchdowns, without a pick. All of his three scoring passes were to one guy – Drake London, who had 118 receiving yards on 9 targets. Though the running was stopped, the Falcons had just 71 yards on the ground.
Drake London, y'all 🤯
— Atlanta Falcons (@AtlantaFalcons) November 2, 2025
CBS | NFL+ pic.twitter.com/jedikJXW52
The Colts felt the Steelers’ defense and learned what it’s like to play against AFC North teams on the road. The top offense in the NFL was limited to only 20 points, having 6 turnovers.
Daniel Jones was terrible, as the Steelers harassed the QB, who had 5 of the mentioned 6 turnovers. Jones threw 3 picks and had two fumbles, being sacked 5 times and hit 6.
Falcons vs. Colts Head to Head
The result in the series is 15-3 in favor of the Colts. The Last game was in 2023, when the Falcons won 29-10.
Falcons vs. Colts Predictions
The Atlanta Falcons have a solid defense, yet they are very unstable. Meanwhile, Jonathan Taylor had only 45 yards against the Steelers, which was the reason why Jones didn’t have any options and had to be one-dimensional. Against the Falcons, he should be better, and that should move the entire Colts’ offense. It’s why we pick Indianapolis to cover a 6.5-point spread.
- Free NFL Picks: Colts -6.5
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