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Expert prediction

NFL Week 10: Detroit Lions vs. Washington Commanders Preview, Odds, Picks (Nov 9)

  • Nikola Velickovic
  • Nov 5, 2025 at 12:08 PM EST

Pick rationale

Analysis & key factors

  • Lions vs. Commanders total is set at 49.5 points.
  • Detroit is the second-best offense in the NFL, 29.9 points per game.
  • Jayden Daniels is out for the Commanders

The Lions lost last weekend, while the Commanders lost their past 4 matches. Additionally, they will be without Jayden Daniels, who has a hurt elbow.

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How to Watch

  • When: Sunday, November 9, 4:25 pm ET
  • Where: Northwest Stadium, Landover, Maryland
  • How to Watch: FOX

Lions vs. Commanders Odds

TeamMoneylineSpreadTotals
Lions-600-9.548.5
Commanders+400+9.548.5

Game Preview

The Vikings shocked Ford Field, beating the Lions 27-24, inflicting their second defeat in the past three games. Nothing worked for the Lions, who had a miserable 65 rushing yards. And not just that. David Montgomery, the leading running back, had a fumble.

Jared Goff threw for 284 passing yards and two touchdowns. Goff’s performance was ok, but his O-Line didn’t protect him well, allowing 5 sacks for 44 negative yards.

As for the Commanders, they have suffered four straight losses, with the previous three by 20 points or more. This indicates a severe crisis in Washington, one that could ruin their season.

On top of everything, Jayden Daniels is injured and won’t be able to help in this contest. So, the Commanders are on a downward slope, their best player is out, and there’s a negative atmosphere around the team, ahead of the crucial part of the campaign.

Lions vs. Commanders Head to Head

After 48 matches, the Commanders lead the series 32-16. Their last game was in January this season, the NFC Divisional Game, which the Commanders won 45-31.

Lions vs. Commanders Predictions

Without Daniels, the hosts are a mediocre team, plus, they have various problems when it comes to their performance, even with the starting QB on the field. Lions should win here and cover an 8.5-point spread.

Free NFL Picks: Lions -8.5

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