Expert prediction
NFL Week 10: Pittsburgh Steelers vs. LA Chargers Preview, Odds, Picks (Nov 9)
- Nikola Velickovic
- Nov 6, 2025 at 2:41 AM EST
Pick rationale
Analysis & key factors
- Steelers vs. Chargers odds favor LA at -145.
- This is Week 10 Sunday Night Football.
- The total for this event is 44.5 points.
The AFC clash between the Steelers and the Chargers highlights this Sunday. It’s a very important event between two direct postseason contenders, and it just might have a massive impact on the playoff picture.
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How to Watch
- When: Sunday, November 9, 8:20 pm ET
- Where: SoFi Stadium, Inglewood, California
- How to Watch: NBC
Steelers vs. Chargers Odds
Game Preview
It’s notable to say that the Steelers’ defense finally showed up and that it was the reason why Pittsburgh defeated the Colts last weekend, 27-20. Jonathan Taylor was stopped at only 45 rushing yards, while Daniel Jones had three intercepted passes and two lost fumbles.
On the other hand, with just 203 passing yards and one TD pass, Aaron Rodgers managed to lead his team to a win. Also, Jaylen Warren had two rushing touchdowns. The Steelers’ run game remains ineffective, gaining only 38 yards on the ground against the Colts.
Sunday Night marks the first ever matchup between Aaron Rodgers & Justin Herbert.#Steelers #Chargers @SNFonNBC #BOLTUP pic.twitter.com/XMvSvYjq45
— Chargers Country (@ChargersCountry) November 5, 2025
The Chargers are back, winning three of the last four. We must note that the schedule was working in their favor, meeting weaker teams on the road (Dolphins and Titans) and struggling ones at home (Vikings).
Their passing defense ranks third in the NFL, allowing 177.1 yards per game. This will be a huge challenge for Rodgers, and we can’t wait to see how the 4-time MVP handles the LAC’s secondary.
Steelers vs. Chargers Head to Head
Pittsburgh leads the series 25-11, with the last meeting in the previous season, 20-10 for the Steelers in Pittsburgh.
Steelers vs. Chargers Predictions
Pittsburgh has been inconsistent, though; their rivals were far, far stronger than the Chargers’. This should be a battle of two good defenses, where the matchups favor the defensive units over the offense. Our pick would be under 44.5 points.
- Free NFL Picks: Under 44.5 points
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