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Expert prediction

NFL Week 16: LA Rams vs. Seattle Seahawks Preview, Odds, Picks (Dec 18)

  • Nikola Velickovic
  • Dec 15, 2025 at 5:23 PM EST

Pick rationale

Analysis & key factors

  • Rams vs. Seahawks odds are even.
  • This is the battle for the NFC West title and the No.1 seed in the NFC.
  • Rams beat Seattle 21-19 in Week 11.

A lot is at stake in this Thursday Night Football. Whoever wins here will be very close to securing the NFC West title and also, the No.1 seed in the NFC.

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How to Watch

  • When: Thursday, December 18, 8:15 pm ET
  • Where: Lume Field, Seattle, Washington
  • How to Watch: Prime Video

Rams vs. Seahawks Odds

TeamMoneylineSpreadTotals
Rams-110-1.544.5
Seahawks-110+1.544.5

Game Preview

A big problem for Sean McVay will be Davante Adams’ absence. It seems that the NFL’s leading receiver in touchdowns (14 so far) won’t be able to play due to his hamstring injury. That’s a huge blow, meaning that Puka Nacua has to be even better now. This guy had 181 receiving yards against the Lions.

A 41-34 win over the Lions was a big boost for the Rams, who are 11-3 now. LAR were behind in this one, yet showed the fighting mentality, flipped the score to eventually triumph. Kyren Williams had 78 rushing yards for 2 touchdowns, while Blake Corum had 71 for one.

Philip Rivers and the Colts gave the Seahawks a hard time last weekend. Seattle triumphed 18-16, with Jason Myers kicking a 56-yard field goal for the win. In fact, the Seahawks didn’t score a single touchdown, and all the points came from Myers, who was 6/6.

Sam Darnold threw for 271 passing yards, and Jaxson Smith-Njigba was his top target with 113 receiving yards. Meanwhile, the run game was terrible, having generated only 50 yards.

Rams vs. Seahawks Head to Head

A month ago in Week 11, the Rams won at home, 21-19. It was a wild one: the Rams had 4 interceptions, and the Seahawks had a chance to win, but Myers missed a long FG. Overall, it’s 28-both in the all-time series.

Rams vs. Seahawks Predictions

If the Seahawks’ run doesn’t show up, this will be a challenging game for them. The Rams are slightly less fluid right now, yet they are still winning. And even though many believe that if Adams isn’t playing, this team might lose, we still think they are a better unit than the Seahawks right now. Why? Because their QB is far better.

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