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Expert prediction

NFL Week 16: Minnesota Vikings vs. New York Giants Preview, Odds, Picks (Dec 21)

  • Nikola Velickovic
  • Dec 17, 2025 at 5:58 AM EST

Pick rationale

Analysis & key factors

  • Vikings vs. Giants odds favor Minnesota by 3 points.
  • The TOTAL went under in 5 of Minnesota’s last 6 games.
  • New York Giants have 8 straight losses.

The Minnesota Vikings woke up late and missed their playoff train. Meanwhile, that’s long known for the Giants, who had one disastrous season.

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How to Watch

  • When: Sunday, December 21, 1 pm ET
  • Where: MetLife Stadium, East Rutherford, New Jersey
  • How to Watch: FOX

Vikings vs. Giants Odds

TeamMoneylineSpreadTotals
Vikings-155-343.5
Giants+130+343.5

Game Preview

The Vikings have back-to-back victories, and if they had woken up sooner, the playoffs would still be in reach. After demolishing the Commanders in Minneapolis, 31-0, they would beat the Dallas Cowboys 34-26. In Dallas.

JJ McCarthy looked solid with 250 passing yards, two touchdowns, and one intercepted pass. The Vikes’ QB had 15 rushing yards for one touchdown too. Jalen Nailor caught two touchdown receptions.

Giants are losing and possibly tanking the season in search of the No.1 pick at the upcoming NFL draft. The most recent loss was to a division rival, the Washington Commanders at home, 29-21.

New York had 384 total yards, but in the key moments, their defense couldn’t hold on, despite forcing two turnovers by the Commanders. Jaxson Dart had 246 passing yards, two touchdowns, and one interception, and he ran for 63 more yards.

Vikings vs. Giants Head to Head

Giants and Vikes met 32 times, and the Vikings lead the all-time series, 19-13. The last match was in the 2024 campaign when the Vikings won 28-6 at MetLife.

Vikings vs. Giants Predictions

It’s safe to say the Vikes are in solid shape, probably better than the Giants. However, we will focus on efficiency, with the total line set at 50.5 points. This is a clear OVER for us, as 8 of the Giants’ last 9 games went OVER and Minnesota has been on a recent run.

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